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Intro to Global Health, Chapter 4 (Quiz Review)

front 1

health system responsiveness

(ie. what does a health system need to be responsive?)

back 1

1) data

2) descriptive statistics

3) measurement tools and surveillance systems

front 2

descriptive statistics

back 2

mean, median, range, standard deviation of data set, etc.

- prevalence of conditions / risk factors

- incidence of new cases

- outcomes

front 3

infant mortality rate

back 3

number of deaths of infants (<12 months) per 1,000 live births, measured annually

front 4

life expectancy at birth

back 4

average number of years a new baby can expect to live if current mortality trends continue

front 5

neonatal mortality rate

back 5

number of deaths of neonates (<28 days) per 1,000 live births, measured annually

front 6

neonate mortality rate statistics

back 6

~4 per 1,000 in high-income countries

~40 per 1,000 LMICs

front 7

under-5 mortality rate (child mortality rate)

back 7

number of deaths of children under 5 per 1,000 live births, measured annually

front 8

under-5 mortality rate (child mortality rate) statistics

back 8

~3-5 per 1,000 in high-income countries

~200 per 1,000 LMICs

captures deaths among children aged 0-59 months

front 9

maternal mortality ratio

back 9

measure of the risk of death associated with childbirth

number of women who die each year as a result of pregnancy, labor, delivery, or within 42 days after delivery, per 100,000 women who deliver a live child

front 10

2023 maternal mortality ratio data

back 10

CA - 4/100,000

MA - 8.4/100,000

LA - 58.1/100,000

front 11

global MMR

back 11

declined from 341 to 211 / 100,000 deaths between 2000 & 2017

front 12

which region has the largest percent reduction of MMR of any region (59%)

back 12

South Asia

also - SSA (39%) was large

front 13

which region has the highest MMR in the world? (2017)

back 13

South Sudan

1,150 / 100,000

front 14

why is MMR measured per 100,000 but neonatal morality and under-5 mortality are measured per 1,000?

back 14

it's relatively rare compared to child mortality / neonatal mortality rates

produces a more meaningful, less fractional number

front 15

fertility rate

back 15

number of births per woman

front 16

global average fertility rate

back 16

~2.3

front 17

highest fertility rate? (2024)

back 17

Niger

6.6

front 18

lowest fertility rate? (2024)

back 18

Hong Kong

0.8

front 19

morbidity

back 19

sickness

front 20

mortality

back 20

death

front 21

mortality rate

back 21

annual number of deaths per 100,000 population

front 22

disability

back 22

long-term or short-term reduction in functional capacity

front 23

prevalence

back 23

number of people with condition X at any given time

cross-sectional in nature

front 24

incidence rate

back 24

number of new cases over time per a given population that's at risk

front 25

disability-adjusted life year (DALY)

back 25

a measure of losses due to illness, disabilities, and premature death

- accounts for loss due to death and disability

- requires data about prevalence and incidence

Mortality + Morbidity

front 26

goal of health policy

back 26

avert DALYs in the most cost-effective way

front 27

health-adjusted life expectancy (HALE)

back 27

the number of years one can expect to live in good health

front 28

risk factor

back 28

an entity (characteristic, environment, behavior, etc.) that is known to be associated with a health issue

front 29

health professionals seek to ______ risk factors

back 29

minimize

front 30

_______ is the lead risk factor for death and disability in high-income countries

back 30

Smoking

front 31

malnutrition

back 31

a leading risk factor worldwide (too much, not enough, not the right kind of nutrition)

front 32

categories covered in global burden of disease study (GBD project)

back 32

- infections and perinatal and maternal conditions

- NCDs

- injuries and accidents

(grouped into 8 global regions - established market economies)

front 33

findings: global burden of disease study

back 33

- high premature mortality in impoverished regions

- lack of good data

- NCDs and injuries play a major role (infectious diseases also critical component)

- inequities among regions are enormous

- findings can be very different for mortality versus for DALYs

front 34

epidemiologic transition "ages"

back 34

1) age of pestilence and famine

2) age of receding pandemics

3) age of degenerative and manmade diseases

4) age of delayed chronic diseases

front 35

limitations of the epidemiologic transition model

back 35

1) diseases do not occur in a stepwise fashion (in contrast to what the model states)

2) disease burden is diverse in all countries

3) health systems in all countries are needed that can address a variety of health issues

4) treatment often is prevention, so healthcare systems need to be able to provide treatment

front 36

cost-effectiveness

back 36

1) formula proposed in '77 by Weinstein and Stason

2) for intervention to be cost-effective, its cost should be no more than 3x the per capita health costs

3) limited impoverished countries to interventions $5-15 per patient per year

front 37

limitations of cost-effectiveness

back 37

1) cheap interventions fail to address the actual burden of disease, out-of-pocket costs, & other costs the patient experiences (also - doesn't address other factors that negatively impact health)

2) fixed costs in cost-effectiveness models that are planned for 5-10 years out fail to account for cost changes

3) too little money allocated for health in impoverished countries; failing to provide healthcare is a moral issue

front 38

the epidemiologists's bathtub

back 38

prevalence = water in bathtub

water leaking out = death

recovery = water evaporating from tub

incidence = faucet putting water into the tub

front 39

'90 burden of disease (measured in DALYs)

back 39

1) diarrhea and common infectious diseases (557.39 million)

2) neonatal disorders (277.79 million)

3) cardiovascular diseases (266.82 million)

(4. cancers, 5. other NCDs)

front 40

'00 burden of disease

back 40

1) diarrhea and common infectious diseases (418.8 million)

2) cardiovascular diseases(300.06 million)

3) neonatal disorders (253.16 million)

(4. cancers , 5. HIV/AIDS and TB)

front 41

'10 burden of disease

back 41

1) cardiovascular diseases (329.07 million)

2) diarrhea and common infectious diseases (295.21 million)

3) neonatal disorders (219.25 million)

(4. cancers , 5. HIV/AIDS and TB)

front 42

2019 burden of disease

back 42

1) cardiovascular disease (393.11 million)

2) cancers (251.39 million)

3) neonatal disorders (185.89 million)

(4. other NCDs, & 5. respiratory infections & TB)

front 43

on the decline over time ('90 - '19), global burden of disease

back 43

- neonatal disorders

- respiratory infections and TB

- enteric infections

- malaria & neglected tropical diseases

- HIV/AIDS and STIs

- other infectious diseases

- nutritional deficiencies

- maternal disorders

front 44

on the rise over time ('90 - '19), global burden of disease

back 44

- cardiovascular disease

- cancers

- musculoskeletal disorders

- diabetes and kidney disease

- mental disorders

- respiratory diseases

- neurological disorders

- digestive diseases

- skin diseases

- substance use disorders

- conflict and terrorism

front 45

staying about the same, global burden of disease

back 45

- unintentional injuries

- transport injuries

- self-harm

- interpersonal violence

- natural disasters

front 46

burden of disease

back 46

quantity of diseases and conditions and their impact on a population

- assessing this = attempting to build systems of care to achieve targets in SDGs

front 47

Global Burden of Disease project ('90)

back 47

quantifies the impact of diseases worldwide on a regular basis

front 48

epidemiological transition

back 48

observed shift in the types of diseases that affect populations as economic conditions improve

- used disease burden to help countries of differing economic strata to assign health priorities

front 49

Disease Control Priorities (DCP) project

back 49

burden of disease in impoverished countries impede economic development -- need to address this

prioritize interventions with greatest impact on burden of disease impoverished communities

(uses cost-effectiveness analyses to help policymakers set priorities in national health systems)

front 50

health system responsiveness x burden of disease

back 50

the health of a population must be measured and understood if the health system is to appropriately respond

front 51

reasons to quantify the burden of disease

back 51

planning, policymaking, design of delivery systems, and program evaluation

front 52

disease

back 52

refers to conditions, illnesses, and injuries

front 53

burden

back 53

refers to the impact of disease on a population

front 54

disease surveillance

back 54

measurement of conditions

front 55

why insufficient data to estimate burden of disease early on?

back 55

1) never reach medical care (get sick and die at home)

2) facilities don't have adequate diagnostic capabilities (causes of illnesses remain unknown)

3) record keepers in short supply (insufficient data to estimate BOD)

front 56

'92, World Bank commissions WHO to quantify global burden of disease

back 56

published a series of papers in the Lancet

front 57

sequelae

back 57

consequences of diseases

- GBD sought to characterize this

front 58

leading causes of death (wealthy versus impoverished countries) - 2021

back 58

wealthiest quartile

1) cardiovascular disease

2) cancer

3) chronic respiratory diseases

impoverished quartile

1) cardiovascular disease

2) respiratory infections and TB

3) maternal and neonatal

front 59

age of pestilence and famine

back 59

- high mortality rate in population

- caused by infectious diseases and starvation

low life expectancies

front 60

age of receding pandemics

back 60

reductions in mortality (esp. young children and infants)

life expectancy increase w/ improved access to food, clean water, and infrastructure

front 61

age of degenerative and manmade diseases

back 61

total fertility rate declines as infant mortality continues to fall

major causes of death = NCDs (cancer, diabetes)

front 62

age of delayed chronic diseases

back 62

reductions in mortality, old age, and primary prevention of chronic diseases (promotion of exercise and healthy diets)

front 63

three dependent inputs for prioritization (GBD project)

back 63

1) understanding types of diseases and overall burden within a country

2) design of health system to respond to need of population

3) ability of govt to set priorities, ability to use instruments at their disposal

*choosing interventions that could be supported within the confines of their health budgets*