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Chapter 66 ADHD

front 1

Most common neurodevelopmental disorder in children, occurring almost twice as often in boys compared to girls

back 1

ADHD

front 2

ADHD is characterized by symptoms of

back 2

inattention, hyperactivity and impulsivity

front 3

What catecholamine can play a role in ADHD

back 3

defects in the dopamine pathways that regulate reward anticipation and emotion self-regulation

front 4

Primary treatment of ADHD

back 4

stimulant medication because they raise dopamine and NE levels

front 5

First-line treatment for preschool-aged children (age 4-5 years)

back 5

parent training in behavior management and/or behavioral classroom intervention

front 6

ADHD medications are considered first-line in patients

back 6

≥ 6 years old

front 7

Natural products that can help with ADHD

back 7

Fish oil (improve cognitive function) and melatonin (to help with sleep)

front 8

Long-acting formulations are preferred for children, to help

back 8

maintain more steady symptom control and avoid the need for a dose during the day at school

front 9

Brand name for atomoxetine

back 9

Strattera

front 10

What is the place of therapy for atomoxetine

back 10

can be tried when stimulants do not work well enough (after 2-3 medications)

front 11

Brand name for guanfacine ER

back 11

Intuniv

front 12

Brand name for clonidine ER

back 12

Kapvay

front 13

guanfacine ER and clonidine ER are non-stimulant medications that can be used

back 13

alone or in combination with stimulants

front 14

Which stimulant capsule contents can be mixed in water, orange juice or yogurt

back 14

Vyvanse

front 15

Adderall XR and Ritalin LA capsule contents can be sprinkled on

back 15

a small amount of applesauce

front 16

all stimulants are C-II and must be dispensed with a

back 16

MedGuide

front 17

MOA of stimulants

back 17

blocks the reuptake of NE and dopamine

front 18

Methylphenidate transdermal patch

back 18

Daytrana

front 19

Brand names for methylphenidate

back 19

Ritalin, Concerta, Quillivant, QuilliChew ER, Daytrana

front 20

Brand name for methylphenidate OROS delivery

back 20

Concerta

front 21

How does OROS delivery work

back 21

the outer coat dissolves fast to provide immediate action, and the rest is released slowly (decreases abuse potential)

front 22

How to apply Daytrana

back 22

apply 2 hours before desired effect (or as soon as the child awakens so it starts to deliver prior to school); remove after 9 hours, alternate hips daily

front 23

active isomer of methylphenidate

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dexmethylphenidate

front 24

Brand name of dexmethylphenidate

back 24

Focalin

front 25

prodrug to dexmethylphenidate

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serdexmethylphenidate

front 26

Brand names of dextroamphetamine/amphetamine

back 26

Adderall, Mydayis

front 27

prodrug of dextroamphetamine

back 27

lisdexamfetamine

front 28

Vyvanse formulations

back 28

capsule, chewable tablet

front 29

Brand name for methamphetamine

back 29

Desoxyn

front 30

What formulation is QuilliChew ER

back 30

chewable tablet

front 31

What formulation is Quillivant XR

back 31

oral suspension

front 32

MOA of viloxazine

back 32

selective NE reuptake inhibitor (approved in patients 6 years and older)

front 33

Brand name of viloxazine

back 33

Qelbree

front 34

Stimulants can cause

back 34

increased HR and BP, serious cardiovascular events, insomnia, psychosis, priapism, decreased appetite

front 35

atomoxetine can cause

back 35

liver damage, suicidal ideation, somnolence

front 36

What does ADHD stand for

back 36

Attention deficit hyperactivity disorder