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Fluid, Electrolyte, and Acid-Base Balance, Chapter 26 P Besaw

front 1

Where is the majority of water stored in the human body?

back 1

intracellular fluid (ICF) compartment

front 2

Select the person in the following list who would have the highest percentage of water in his or her body.

back 2

a 6-month-old baby boy

front 3

What solute in body fluids determines most of their chemical and physical reactions?

back 3

electrolytes

front 4

The most abundant cation in intracellular fluid is potassium.

back 4

True

front 5

Which of the following is an electrolyte?

back 5

potassium

front 6

The fluid that bathes the cells found in tissues is called __________.

back 6

interstitial fluid

front 7

What is the most abundant intracellular anion?

back 7

HPO42

front 8

What is the most abundant intracellular cation?

back 8

K+

front 9

What is the most common cation found in the interstitial fluid?

back 9

Na

front 10

Which of the following creates the greatest osmotic pressure?

back 10

H3PO4

front 11

The movement of fluids between cellular compartments ________.

back 11

is regulated by osmotic and hydrostatic forces

front 12

In a given day, what is the typical value for water intake?

back 12

2500 ml

front 13

What accounts for the route through which most fluid is lost in a day?

back 13

urine

front 14

How much water is generated per day from cellular metabolism?

back 14

250 ml

front 15

Which of the following is NOT involved in triggering the thirst mechanism?

back 15

increase in blood pressure

front 16

What receptors does the brain use to detect changes in osmolality?

back 16

osmoreceptors

front 17

What hormone helps to maintain extracellular fluid (ECF) osmolality when concentrations become too high?

back 17

antidiuretic hormone (ADH)

front 18

What type of water imbalance increases the amount of fluid in all compartments?

back 18

hypotonic hydration

front 19

Which of the following conditions promotes edema?

back 19

hypoproteinemia

front 20

What is the hallmark of hypotonic hydration?

back 20

hyponatremia

front 21

Which of the following would NOT be expected to lead to edema?

back 21

hyponatremia

front 22

The role of ADH is to __________.

back 22

increase water reabsorption

front 23

Under normal circumstances, most water is lost in __________.

back 23

urine

front 24

The body's water volume is closely tied to a powerful water "magnet." What magnet is referred to here?

back 24

ionic sodium

front 25

What is the driving force for water intake?

back 25

thirst

front 26

Which of the following is NOT a risk factor for dehydration?

back 26

increased muscle mass

front 27

Which of the following regulates the secretion of K+ into the filtrate?

back 27

aldosterone

front 28

What results from increased levels of aldosterone?

back 28

increased Na+ reabsorption

front 29

Which of the following does NOT impact how much sodium is reabsorbed?

back 29

transport maximum of the renal proximal tubule

front 30

PTH (parathyroid hormone) acts on the __________ to __________ Ca2+ reabsorption.

back 30

DCT; increase

front 31

Potassium balance is controlled mainly by renal mechanisms.

back 31

True

front 32

Which of the following is NOT a hormone involved in water and electrolyte balance?

back 32

thyroxine

front 33

Which hormone raises blood calcium levels?

back 33

PTH

front 34

A patient is discovered to have a strange craving for iron objects. To try to determine the cause, her physician decides to order tests to determine if this patient might have some type of ______.

back 34

anemia

front 35

Which of the following abnormalities would not be observed in a patient who has Addison's disease?

back 35

hypertension

front 36

Hypersecretion of aldosterone results in hypokalemia, which causes hyperpolarization of neurons; this in turn results in ______.

back 36

the need for a stronger than normal stimulus in order to trigger an action potential

front 37

Which of the following is the only logical explanation for why hypocalcemia increases neuromuscular excitability and causes muscle tetany?

back 37

Low plasma calcium ion concentration increases the permeability of neuron membranes to sodium ions, thereby causing depolarization that in turn increases the likelihood of action potentials being generated.

front 38

Starvation would cause which of the following acid-base conditions? Also, determine what type of compensation (metabolic or respiratory) there would be.
Hint 1.

During starvation, the body must break down fats for metabolism, which causes a buildup of ketones in the body.

back 38

metabolic

front 39

A patient is admitted to the hospital with the following plasma values: pH = 7.2, pCO2 = 55 mmHg, and HCO3¯ = 30 mEq/L. What is the acid base imbalance?
Hint 1.

Normal pH = 7.35 to 7.45; normal pCO2 = 35 to 45 mmHg; normal HCO3¯ = 22 to 26 mEq/L

back 39

respiratory acidosis with metabolic compensation

front 40

A patient is admitted to the hospital with the following plasma values: pH = 7.5, pCO2 = 45 mmHg, and HCO3¯ = 30 mEq/L. What is the acid-base imbalance?
Hint 1.

Normal pH = 7.35 to 7.45; normal pCO2 = 35 to 45 mmHg; normal HCO3¯ = 22 to 26 mEq/L

back 40

metabolic alkalosis with no compensation

front 41

A patient is admitted to the hospital with the following plasma values: pH = 7.2, pCO2 = 25 mmHg, and HCO3¯ = 18 mEq/L. What is the acid base imbalance?
Hint 1.

Normal pH = 7.35 to 7.45; normal pCO2 = 35 to 45 mmHg; normal HCO3¯ = 22 to 26 mEq/L

back 41

metabolic acidosis with respiratory compensation

front 42

Diarrhea can lead to which acid/base disturbance? Assuming compensation, would it be a metabolic or respiratory compensation?
Hint 1.

Diarrhea causes a loss of bicarbonate ions.

back 42

metabolic acidosis with respiratory compensation

front 43

Emphysema can lead to which acid/base disturbance? What would be the compensation?
Hint 1.

A patient with emphysema would retain CO2.

back 43

respiratory acidosis; kidneys will retain more HCO3 and excrete H+

front 44

Of the three buffering mechanisms in the body, which is the strongest?
Hint 1.

This system is also the slowest system.

back 44

renal system

front 45

The bicarbonate buffer system is one of the chemical buffer systems of the body. How would the bicarbonate buffer system work if sodium hydroxide were added to a solution?
Hint 1.

The bicarbonate buffer system is a mixture of carbonic acid (weak acid) and its salt sodium bicarbonate (weak base).

back 45

A hydrogen on carbonic acid would dissociate and join the hydroxyl group on the base to form water and sodium bicarbonate.

front 46

The respiratory system is one of the three systems that regulate acid-base balance in the body. How does it work to decrease an acidosis?
Hint 1.

Think about the main function of the respiratory system.

back 46

Carbonic acid is broken down into water and CO2; the CO2 is then exhaled.

front 47

In a respiratory acidosis the kidney would do which of the following?
Hint 1.

The kidney has three basic functions: filtration, reabsorption, and secretion.

back 47

The kidney would reabsorb bicarbonate and secrete hydrogen ions.

front 48

Ingesting too much antacid would cause which of the following acid-base disturbances?
Hint 1.

Sodium bicarbonate is an example of an antacid. Ingestion of bicarbonate would cause which acid-base disturbance?

back 48

metabolic alkalosis

front 49

Vomiting will cause which type of acid-base disturbance?
Hint 1.

Vomiting would cause a loss of HCl acid from the stomach.

back 49

metabolic alkalosis

front 50

Severe anxiety would cause which type of acid-base disturbance? What would be the compensation?
Hint 1.

Anxiety would cause hyperventilation

back 50

respiratory alkalosis; kidneys would excrete HCO3

front 51

Which chemical buffer system is the only important system in the extracellular fluid (ECF) that resists short-term changes in pH?

back 51

bicarbonate buffer system

front 52

In order to buffer a strong acid into a weak acid, which has a less dramatic effect on pH, what chemical should be used as the buffer?

back 52

weak base

front 53

Which of the following does NOT serve as a source of acids in the body?

back 53

aerobic breakdown of glucose

front 54

The most important renal mechanism for regulating acid-base balance of the blood involves __________.

back 54

maintaining HCO3- balance.

front 55

A decrease in blood CO2 levels leads to __________.

back 55

an increase in blood pH

front 56

The primary buffer of the extracellular fluid (ECF) is the __________.

back 56

bicarbonate buffer system

front 57

The most common cause of acid-base imbalance is __________.

back 57

respiratory acidosis

front 58

Which buffer system is the most abundant in the body?

back 58

protein

front 59

Which organs are the ultimate acid-base regulatory organs?

back 59

kidneys

front 60

What is the effect of hyperventilation on pH?

back 60

respiratory alkalosis

front 61

What is the most common cause of acid-base imbalance?

back 61

respiratory acidosis

front 62

Which age group most commonly has fluid, electrolyte, and acid-base balance issues?

back 62

infants