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Chapter 20 -Immunizations

front 1

Which tetanus-containing vaccine requires five doses to be given as a part of the routine childhood vaccine series?

back 1

DTaP

Children should get five doses of DTaP, one dose at each of the following ages: 2, 4, 6, and 15-18 months and 4-6 years. DT does not contain pertussis and is used only as a substitute for DTaP in children who cannot tolerate pertussis vaccine.

front 2

A patient is undergoing a pre-operative evaluation for a splenectomy. Which vaccine is specifically indicated in a patient without a spleen?

back 2

Menactra

front 3

Exposure to which of the following commonly requires administration of immune globulin at the time of vaccination?

back 3

Rabies

front 4

History of Present Illness: this is a 65-year-old male who presents to the emergency department with altered mental status. According to the patient's daughter, he has been confused since yesterday and is now dragging his right side. The patient does not recognize his daughter and he is unable to answer questions related to recent events. He denies chest pain or shortness of breath. The daughter also noticed some blood in the patient's urine this morning.
Past Medical History:

HypertensionPeripheral vascular diseaseCOPDTobacco use (1 PPD)DyslipidemiaDiabetes Chronic kidney disease, stage 2

At discharge, the nurse screens the patient to determine if he is a candidate for any vaccinations. The patient states that he only recently established care with a healthcare provider and cannot recall receiving any vaccinations in the past 20 years. Based on his medical profile, which vaccines would be indicated in this patient? (Select ALL that apply)

back 4

Shingrix, Prevnar 20, Tdap

front 5

Which of the following statements concerning the recombinant vaccine Flublok are correct? (Select ALL that apply.)

back 5

Flubok is an egg-free vaccine

Flubok is approved for use in patients 18 years and older

front 6

A small community pharmacy just received a delivery of influenza vaccines. The pharmacy owner needs to instruct the staff on storage requirements. He should include the following information:

back 6

The stock should be rotated so that the oldest vaccines (earliest expiration dates) are in the front

front 7

Which vaccine is contraindicated in patients with a severe allergy to eggs or gelatin?

back 7

Yellow fever

The yellow fever vaccine should be avoided in patients with severe (life-threatening) allergies to eggs or gelatin.

front 8

History of Present Illness: TH is a 57-year-old male who presents to the ED on February 5 with a decreased level of consciousness. He was found unresponsive on the bathroom floor by his daughter, who came to check on him after a call from the dialysis center that he had missed 2 sessions. She had spoken to him 2 days prior, when he told her he had been to the doctor and gotten prescriptions for Tamiflu and a cough syrup after a positive influenza swab.

Past Medical History: end stage renal disease (anuric), hemodialysis on MWF for 3.5 hours each session, hypertension, osteoarthritis (knees), restless legs syndrome, hypothyroidism

Which vaccinations are indicated for this patient if not otherwise up-to-date? (Select ALL that apply)

back 8

Inactivated influenza vaccine

Tdap

PCV20

front 9

**case above**

When questioned, TH states that he declined the influenza vaccine offered at his dialysis center in the fall because he felt like he was getting a cold. Which of the following is true regarding the influenza vaccine in this patient?

back 9

He should receive a dose of inactivated influenza vaccine prior to discharge

front 10

A 12-month-old child was hospitalized two months ago and received immune globulin for Kawasaki disease. Which vaccine/s would be adversely affected by this treatment if administered today? (Select ALL that apply.)

back 10

Measles, mumps and rubella vaccine

Varicella vaccine

front 11

History of Present Illness: SM is a 36-year-old male who presents to the HIV clinic for a routine appointment. He is doing well and has no major complaints at this time. He states that he uses his albuterol inhaler 4 days per week (about 6 puffs on each of those days) and has been trying over-the-counter medications to manage occasional heartburn.Allergies: sulfa (hives)

Past Medical History: HIV (no history of opportunistic infections)Asthma, Dyslipidemia

Immunization History: annual influenza vaccine (up-to-date), Recombivax-HB (up-to-date), no history of pneumococcal vaccination

Which pneumococcal vaccination recommendation is most appropriate for SM?

back 11

Prevnar 20 x 1

front 12

**case above**

Which vaccine is indicated for SM based on his medical profile?

back 12

Menveo

front 13

A child with sickle cell disease has not been vaccinated for meningococcal disease. Which of the following is true regarding meningococcal disease/vaccine? (Select ALL that apply.)

back 13

Quadrivalent meningococcal vaccines include Menactra and Menveo

The damage to the spleen caused by sickle cell disease puts this patient at risk for meningococcal disease

This patient should receive the MenB vaccine once the turns 10 years old

High-risk populations can be vaccinated starting at 2 months of age

front 14

Which of the following vaccines must be stored in the freezer and require reconstitution with a diluent prior to administration? (Select ALL that apply.)

back 14

Proquad

Varivax

front 15

A 20-year-old female has no evidence of immunity to varicella and is being vaccinated to prevent chickenpox. Which screening question must be asked before administering Varivax?

back 15

Have you ever had a severe reaction to gelatin

front 16

LM, a 29-year-old female, is starting her first job as a hospital pharmacist in September. She completed the hepatitis B vaccine series during pharmacy school but states that she did not receive most childhood vaccines and cannot recall any other vaccinations during adulthood. What vaccines should LM receive today? (Select ALL that apply.)

back 16

Seasonal influenza vaccine

Tdap

Varivax

front 17

When at the health clinic to get influenza vaccines for herself and her 13-month-old daughter, a mother noted on the screening form that her daughter received VAQTA earlier that month. Which of the following statements is true?

back 17

VAQTA is a hepatitis A vaccine

front 18

Select the correct name for the chickenpox vaccine:

back 18

Varivax

front 19

Referring to the figure, which choice best represents the appropriate location for administering the Tdap vaccine?

back 19

B
The Tdap vaccine should be administered intramuscularly into the deltoid muscle.

front 20

On January 20th, a 4-year-old child was hospitalized for 7 days with Kawasaki disease. During the hospitalization, she received 80 mg/kg/day of oral aspirin, 30 mg/kg/day of IV methylprednisolone and IV immune globulin (Privigen). She is scheduled for a visit with her pediatrician on March 10th for routine vaccinations. Which vaccine should not be administered on March 10th given the treatments received during her hospitalization?

back 20

MMR

front 21

HS is a healthy 67-year-old female who presents to her PCP in October. Which vaccine should the pharmacist recommend for HS today?

back 21

Shingrix

front 22

A 52-year-old male comes to his primary care provider for his annual physical examination.

Past Medical History: gout, hypothyroidism

Immunization History:
Hepatitis B series (5 years ago)
Tdap (5 years ago)
Influenza (1 month ago)

Medications: allopurinol 100 mg PO daily, levothyroxine 50 mcg PO daily

Vital Signs: BP 108/70 mmHg, HR 72 bpm, RR 16 bpm, T 98.2°F (36.8°C), Ht 5′ 10″, Wt 80 kg

Laboratory Tests (Fasting):
Glucose 85 mg/dL
Serum creatinine 0.9 mg/dL
Aspartate aminotransferase 16 units/L
Alanine aminotransferase 12 units/L
White blood cells 6,000 cells/mm3
Thyroid-stimulating hormone 1.4 mIU/L
Total cholesterol 180 mg/dL
Low-density lipoprotein 77 mg/dL
High-density lipoprotein 85 mg/dL
Triglycerides 110 mg/dL

Which of the following vaccinations is recommended for this patient at this time?

back 22

Recombinant zoster

front 23

Which of the following patients are eligible to receive the pneumococcal conjugate vaccinePrevnar 20? (Select ALL that apply)

back 23

50 year old male with COPD

68 year old female with hypertension

front 24

FM is a 16-year-old female who presents to the clinic for a follow-up visit with her psychiatrist. She was diagnosed with ADHD as a small child but stopped taking her medications 2-3 years ago. She now feels like she needs to be started back on medication to help her focus with school work.

Allergies: sulfa
VitalsHeight: 5'4" Weight: 120 lbsBP: 110/64 mm Hg, HR: 65 BPM, RR: 18 BPM, Temp: 98.6 F
Past Medical HistoryADHDMajor depressive disorderInsomnia
Medications Prozac 20 mg QHS
Plan Vyvanse 30 mg each morningCatapres 0.1 mg QHSFollow-up in 1 month

It is discovered that FM has not received any doses of the human papillomavirus vaccine. If a dose of Gardasil 9 is administered today, how many additional doses will need to be administered to complete the series?

back 24

2

front 25

History of Present Illness: TP is a 52-year-old African American female who was admitted to the hospital 5 days ago for resection of an abdominal mass.

Allergies: Accupril (cough), cefepime (anaphylaxis)

Past Medical History:
Hypertension
Kidney transplant (cadaveric donor) 6 years ago

Immunization History:
Prevnar 13 and Pneumovax 23 (6 years ago)
Influenza (up-to-date)

During her hospitalization, TP has an immunization screening. Which of the following vaccines should be administered to TP?

back 25

Prevnar 20

front 26

KH approaches the pharmacist in January and asks if her 7-year-old daughter should receive the seasonal influenza vaccination. She notes that her daughter has a severe allergy to eggs. Which statement regarding the administration of an influenza vaccine for KH's daughter is correct?

back 26

If she has not been previously vaccinated for influenza, she should receive two doses spaced four weeks apart

front 27

Choose the correct statements regarding SC administration of vaccines. (Select ALL that apply.)

back 27

Varivax, yellow fever and MMR can be administered subcutaneously

SC injections are administered into the fatty tissues over the triceps

SC injections are administered at a 45-degree angle

SC injections are administered using a needle that is 5/8 inch long

front 28

A small community pharmacy just received a delivery of influenza vaccines. The pharmacist tells the staff to place the FluMist in the refrigerator door to keep it separate from the influenza injections.

Which of the following statements regarding vaccine storage is correct?

back 28

Vaccines should not be stored in the doors of a refrigerator

Vaccines should be stored in the center of the refrigerator

front 29

The manager at a pharmacy ordered 100 single-dose vials of Afluria. He found them stored in the pharmacy's freezer. Choose the correct course of action:

back 29

The vaccine cannot be used; it must be safely discarded

front 30

Which statements regarding vaccine administration timing and spacing are true? (Select ALL that apply.)

back 30

Two live vaccines can be administered on the same day

After the administration of a live vaccine, a 2-week interval is required before an antibody-containing product can be administered

If not given on the same day, wait 4 weeks after the administration of a live vaccine before performing a tuberculin skin test

front 31

HY is a 77-year-old female with diabetes, heart failure and rheumatoid arthritis. She would like to get a flu vaccine while her prescriptions are filled. Which of the following formulations would not be appropriate for her?

back 31

FluMist

front 32

On October 14th, a 13-month-old child was hospitalized for 4 days for a flare of polyarticular juvenile rheumatoid arthritis. During the hospitalization, her rheumatologist administered IV steroids, nonsteroidal anti-inflammatory drugs and Gammagard (intravenous immunoglobulin) to manage the flare. The child is now scheduled for a visit with her pediatrician to catch up on several vaccinations, including Varivax. What is the earliest date that Varivax should be administered to this child?

back 32

January 28th

front 33

JK is a 21-year-old male who presents to the urgent care clinic on June 22 with a puncture wound in his left foot after stepping on a nail when he walked outside barefoot. He remembers getting a tetanus shot at age 14 (it made his arm very sore) but has only gotten a flu shot every year since then. Which of these vaccines would be an appropriate selection to administer at this time? (Select ALL that apply.)

back 33

Td and Boostrix

front 34

VR is 20 weeks pregnant with her second child. She is unsure what childhood vaccines she received and is certain that she has not been vaccinated for anything in at least fifteen years. Which vaccines are recommended for VR during her pregnancy? (Select ALL that apply.)

back 34

Tdap and Afluria (during flu season)

front 35

A 62-year-old female patient came into the pharmacy to get an influenza shot. It was her first time receiving the annual vaccine. Three days later, she came back complaining of a hacking cough, mild weakness, stuffy nose and a sore throat. She is afebrile and reports no muscle aches or pains. She states the shot gave her the flu. What is the most likely reason for the patient's illness?

back 35

She has a cold

front 36

Select the correct information for the Varivax vaccine.

back 36

Once drawn up in a syringe, the vaccine must be used quickly

front 37

Chief Complaint: "I'm here for my flu vaccine but my stomach hurts"
History of Present Illness: ZB is a 66-year-old white female who presents to her PCP with a 2-week history of gastric pain that is worse at night and in between meals. She describes a burning pain that goes from a "9 out of 10" to a "5 out of 10" when she eats.
Allergies: penicillin (swollen tongue)
Past Medical History: hypertension, type 2 diabetes, dyslipidemia, osteoporosis, anxiety, chronic pain
Social History: quit smoking 20 years ago (previous 15-year pack history), drinks 1 vodka and soda each night while playing cards with friends at the retirement home

Select the correct administration instructions for the vaccine that ZB is scheduled to receive today.

back 37

Deltoid, 90 degree angle

front 38

ZB will be receiving two pneumococcal vaccines. Which of the following regimens represents the correct vaccines, sequence and interval?

back 38

PCV15 today, PPSV23 in 1 year

front 39

The Shingrix vaccine is recommended for which of the following patients?

back 39

A 52 year old adult with hypertension

front 40

Which vaccine can cause a false-positive reaction to the Tuberculin Skin Test (TST)?

back 40

Bacille Calmette-Guerin (BCG)