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16 notecards = 4 pages (4 cards per page)

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Thyroid Drugs

front 1

Drug Class of Levothyroxine

back 1

Thyroid Hormone

front 2

Levothyroxine Sodium (T4)

back 2

1. Synthroid

2. Levoxyl

3. Levothroid

front 3

FDA Indication

back 3

Hypothyroidism

front 4

Mechanism of Action Levothyroxine

back 4

The exact MOA of Levothyroxine is unknown, however, when administered, T4 diffuses into the cell nucleus and binds to thyroid receptor proteins attached to DNA resulting in:

1. a regulation of growth and development

2. an increases in metabolic rate

3. inhibition of the secretion of thyrotropin by the pituitary

4. various effects on lipid and carbohydrate metabolism

front 5

Adverse Effects of Levothyroxine

back 5

Extremely rare other than those adverse effects occurring due to overdosing.

front 6

Overdosing from Levothyroxine can result in a hypermetabolic state with the following symptoms:

back 6

1. Fever

2. HypOglycemia

3. HF

4. Fluid loss

5. Tachycardia

6. Anxiety

7. Insomnia

front 7

Contraindication of Levothyroxine

back 7

Uncorrected adrenal insufficiency

front 8

BBW of Levothyroxine

back 8

When used off-label for obesity or weight reduction Levothyroxine can cause extreme toxicity.

  • NOT to be used to treat obesity and weight loss

front 9

Patient Counseling Tips for Levothyroxine

back 9

no data

front 10

Levothothyroxine must be taken with _________

back 10

Water

NOTE: Water should be drank consistently for at least 60 minutes for better absoprtion.

front 11

Take Levothyroxine ____ minutes before breakfast

back 11

60 minutes

front 12

TRUE or FALSE

Different brands of Levothyroxine may NOT work the same.

back 12

TRUE

front 13

If taken at bedtime, it MUST be take at least _____ hours after last meal.

back 13

3 hours

front 14

How often should thyroid levels be tested when receiving thyroid suppplementation?

back 14

Annually

front 15

The full effect of Levothyroxine is usually delayed. How long does it usually take for the full effect of Levothyroxine to be observed?

back 15

1-2 months

front 16

TRUE or FALSE

Levothyroxine can be taken 60 minutes before breakfast OR at bedtime (at least 3 hours after last meal)

back 16

TRUE