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32 notecards = 8 pages (4 cards per page)

Viewing:

adrenergic agonists and antagonists; cholinergic agonists and antagonists

front 1

adrenergic agonist drugs stimulate what system? what is the primary neurotransmitter

back 1

  • stimulate the SNS (fight or flight)
  • norepinephrine

front 2

define catecholamines. what response can it produce?

back 2

they are chemical structure of a substance that can produce a sympathomimetic response

front 3

sympathomimethic: adrenergic agonist

  • what is the MOA of epinephrine?

back 3

acts on alpha1, beta1 and 2 receptors causing vasoconstriction

front 4

what is epinephrine used for

back 4

anaphylaxis reaction, bronchospasm, cardiac arrest, cardiac resuscitation

front 5

the nurse know epinephrine is working when ____

back 5

BP goes up and the patient can easily breathe

front 6

what are some S/S you will see if a patient is having a SE/AR to epinephrine

back 6

tachycardia, HTN, tissue death, agitation

front 7

what beta-adrenergic agonist works on the lungs to dilate and relax muscles?

back 7

albuterol. it relaxes bronchial smooth muscle, causing bronchodilation

front 8

uses of albuterol

back 8

asthma and prophlaxis for bronchospasm

front 9

what are some SE of albuterol?

back 9

tremors, dizziness, tachycardia, HTN, dysrhythmias

front 10

central-acting alpha agonist

  • clonidine MOA and use?

back 10

  • produce vasodilation
  • HTN

front 11

what are some SE/AR of taking clonidine

back 11

headache, drowsiness, ejaculation dysfunction, elevated liver enzymes

front 12

drugs that block the effects of adrenergic neurotransmitters are______. what do they block?

back 12

adrenergic antagonist or adrenergic blockers. they either block alpha or beta receptors

front 13

your patient is experiencing tachycardia, HTN, urinary retention, etc. what type of drug will you give?

back 13

an adrenergic antagonist

front 14

effects of adrenergic blockers on receptors

back 14

front 15

beta 1-adrenergic blockers

  • MOA of atenolol. what does it suppress?

back 15

  • blocks beta1 adrenergic receptor sites.
  • it suppresses the RAAS system

front 16

atenolol is used for______

back 16

HTN, angina, and AMI

front 17

what should the nurse monitor closely after administering atenolol?

back 17

BP and pulse.

front 18

what are some SE/AR a patient will experience while taking atenolol

back 18

drowsiness, dizziness, erectile dysfunction, hypotension, bronchospasm

front 19

cholinergic agonist are drugs that______

what do they mimic?

back 19

  • stimulate the parasympathetic nervous system
  • mimic the action of acetylcholine

front 20

cholinergic: parasympathomimetic

  • bethanechol chloride stimulates_____

back 20

the cholinergic receptors

front 21

bethanechol chloride is used for____

back 21

to increase urinary in urinary retention and neurogenic bladder

front 22

what are the SE/AR of taking bethanechol

back 22

tachycardia, weakness, bronchospasm, cholinergic crisis

front 23

cholinergic crisis is the overstimulation of what? what will a patient in a cholinergic crisis experience?

back 23

  • overstimulation of cholinergic system.
  • bronchospasm, tachycardia, weakness.

front 24

cholinergic antagonists inhibit the actions of____by blocking_____

back 24

acetylcholine; the receptors

front 25

cholinergic antagonists have effects on what body systems?

back 25

  • heart
  • respiratory tract
  • GI tract
  • urinary system
  • eyes
  • exocrine glands

front 26

what anticholinergic or parasympatholytic drug inhibits acetylcholine by occupying the receptors

back 26

atropine

front 27

what is atropine used for

back 27

pre-op medication to reduce salivation, increase HR, dilate pupils

front 28

SE/AR of atropine

back 28

tachycardia, pulmonary edema, laryngospasm, anticholinergic toxicity

front 29

atropine is contraindicated in______

back 29

renal and hepatic disorder, COPD, heart failure

front 30

the nurse know her patient is going through an anticholinergic toxicity when____

back 30

front 31

anticholinergic agents

  • benztropine MOA
  • USE
  • AE

back 31

  • block cholinergic receptors, dopamine uptake
  • decrease involuntary symptoms of Parkinsonism
  • tachycardia, urinary retention, hallucinations, paresthesia

front 32

anticholinergic agen

  • tolterodine tartrate MOA
  • USE
  • AE

back 32

  • blocks cholinergic receptors in urinary bladder
  • decrease urinary frequency, urgency, incontinence
  • chest pain, tachycardia, peripheral edema, blurred vision, confusion