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Campbell Biology, 11th Ed chapters 11, 12

front 1

Cytokinesis often, but not always, accompanies _____.

A) Telophase

B) Anaphase

C) Metaphase

D)Interphase

E) Prometaphase

back 1

A

front 2

Chromosomes become visible during _____.

A)metaphase

B)interphase

C) prometaphase

D)anaphase

E) prophase

back 2

E

front 3

Centromeres divide and sister chromatids become full-fledged chromosomes during _____.

A)metaphase

B)interphase

C) prometaphase

D)anaphase

E) prophase

back 3

D

front 4

Spindle fibers attach to kinetochores during _____.

A)metaphase

B)interphase

C) prometaphase

D)anaphase

E) prophase

back 4

C

front 5

This animation illustrates the events of _____.

A)metaphase

B)interphase

C) prometaphase

D)anaphase

E) prophase

back 5

D

front 6

This animation illustrates the events of _____.

A) cytokinesis as it occurs in animal cells

B)prophase

C)prometaphase

D)cytokinesis as it occurs in plant cells

E) metaphase

back 6

A

front 7

This animation illustrates the events of _____.

A)metaphase

B)interphase

C) prometaphase

D)anaphase

E) prophase

back 7

E

front 8

This animation illustrates the events of _____.

A)anaphase I

B) anaphase II

C) prophase II

D) interphase

E)telophase I and cytokinesis

back 8

B

front 9

This animation illustrates the events of _____.

A) prophase I
B) telophase II and cytokinesis
C) anaphase II
D) prophase II
E) telophase I and cytokinesis

back 9

C

front 10

Gametes are produced by _____.
A) meiosis
B) fertilization
C) mitosis
D) the cell cycle
E) asexual reproductionMeiosis

back 10

A

front 11

A diploid organism whose somatic (nonsex) cells each contain 32 chromosomes produces gametes containing _____ chromosomes.
A) 16
B) 8
C) 64
D) 30
E)32

back 11

A

front 12

Meiosis I produces _____ cells, each of which is _____.

A) four ... diploid
B) two... diploid
C) two... identical to the other
D) four ... haploid
E) two ... haploid

back 12

E

front 13

Meiosis II typically produces _____ cells, each of which is _____.

A) four ... diploid
B) two... diploid
C) two... identical to the other
D) four ... haploid
E) two ... haploid

back 13

D

front 14

During prophase, a homologous pair of chromosomes consists of _____.

A) ONE chromosome and two chromatids

B)ONE chromosome and four chromatids

C)TWO chromosomes and two chromatids

D)TWO chromosomes and four chromatids

E)four chromosomes and two chromatids

back 14

D

front 15

This animation illustrates the events of _____.

A) Telophase

B) Anaphase

C) Metaphase

D)Interphase

E) Prometaphase

back 15

E

front 16

This animation illustrates the events of _____.

A) Telophase

B) Anaphase

C) Metaphase

D)cytokinesis as it occurs in plant cells

E) aNaphase

back 16

D

front 17

This animation illustrates the events of _____.

A) Telophase

B) Anaphase

C) Metaphase

D)Interphase

E) Prometaphase

back 17

A

front 18

Which of these phases encompasses all of the stages of mitosis?

A)

B)

C)

D)

E)

back 18

E

front 19

Which of these cells is (are) haploid?

A) C AND D

B) A AND B

C)B AND A

D)C AND D

E)D AND B

back 19

A

front 20

Which of the following is true of kinetochores?

Which of the following is true of kinetochores?

A)They interdigitate at the cell's equator and then move apart, causing the cell to elongate.

B)They are the primary centromere structures that maintain the attachment of the sister chromatids prior to mitosis.

C)They are sites at which microtubules attach to chromosomes.

D)they attach to the ring of actin along the cytoplasmic surface of the plasma membrane, causing the actin to contract to form the cleavage furrow

E) They are located at the center of the centrosome; their function is to organize tubulin into elongated bundles called spindle fibers.

back 20

C

front 21

In some organisms, such as certain fungi and algae, cells undergo the cell cycle repeatedly without subsequently undergoing cytokinesis. What would result from this?

A)a decrease in chromosome number

B)large cells containing many nuclei

C)division of the organism into many cells, most lacking nuclei

D)a rapid rate of gamete production

E)inability to duplicate DNA

back 21

B

front 22

22) Cells will usually divide if they receive the proper signal at a checkpoint in which phase of the cell cycle?

A)G2

B)S

C)M

D)G1

E)CYTOKINESIS

back 22

D

front 23

230Which of the following is true of benign tumors, but not malignant tumors?

A)They migrate from the initial site of transformation to other organs or tissues.

B)They remain confined to their original site

C)They are the result of the transformation of normal cells.

D)They can divide indefinitely if an adequate supply of nutrients is available.

E)They have an unusual number of chromosomes.

back 23

B

front 24

24)Through a microscope, you can see a cell plate beginning to develop across the middle of a cell and nuclei forming on either side of the cell plate. This cell is most likely

A)a plant cell in the process of cytokinesis.

B)an animal cell in the process of cytokinesis.

C)a plant cell in metaphase.

D)a bacterial cell dividing.

E)an animal cell in the S phase of the cell cycle.

back 24

A

front 25

25)In the cells of some organisms, mitosis occurs without cytokinesis. This will result in

A)destruction of chromosomes.

B)cell cycles lacking an S phase.

C)cells lacking nuclei.

D)cells that are unusually small.

E)cells with more than one

back 25

E

front 26

26)Which of the following does not occur during mitosis?

A)condensation of the chromosomes

B)separation of sister chromatids

C)separation of the spindle poles

D)replication of the DNA

E)spindle formation

back 26

D

front 27

27)The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

A)spindle formation

B)cleavage furrow formation and cytokinesis

C)spindle attachment to kinetochores

D)cell elongation during anaphase

E)DNA synthesis

back 27

B

front 28

28) Human gametes are produced by _____

A)meiosis

B) asexual reproduction

C)mitosis

D) fertilization

E) the cell cycle

back 28

A

front 29

29)Normal human gametes carry _____ chromosomes.

A)46

B)23 Pairs of

C)46 pairs of

D)5

E)23

back 29

E

front 30

30)Of the following, a receptor protein in a membrane that recognizes a chemical signal is most similar to

A) RNA specifying the amino acids in a polypeptide.
B) genes making up a chromosome.
C) a particular metabolic pathway operating within a specific organelle.
D) the active site of an allosteric enzyme in the cytoplasm that binds to a specific substrate.
E) an enzyme with an optimum pH and temperature for activity.

back 30

D

front 31

31)During which stage of mitosis do spindle microtubules first attach to kinetochores?
A) metaphase
B) prophase
C) prometaphase
D) anaphase
E) telophase

back 31

C

front 32

32)Which of the following best describes how chromosomes move toward the poles of the spindle during mitosis?
A) Motor proteins of the kinetochores move the chromosomes along the spindle microtubules.
B) The chromosomes are "reeled in" by the contraction of spindle microtubules, and motor proteins of the kinetochores move the chromosomes along the spindle microtubules, and non-kinetochore spindle fibers serve to push chromosomes in the direction of the poles.
C) Non-kinetochore spindle fibers serve to push chromosomes in the direction of the poles.
D) The chromosomes are "reeled in" by the contraction of spindle microtubules, and motor proteins of the kinetochores move the chromosomes along the spindle microtubules.
E) The chromosomes are "reeled in" by the contraction of spindle microtubules.

back 32

A

front 33

33)A diploid organism whose somatic (nonsex) cells each contain 32 chromosomes produces gametes containing _____ chromosomes.

A)8

B)32

C)30

D)16

E)64

back 33

D

front 34

34)What number and types of chromosomes are found in a human somatic cell?

A)45 autosomes and 1 sex chromosome

B)44 autosomes and 2 sex chromosomes

C)21 autosomes and 2 sex chromosomes

D)22 autosomes and 1 sex chromosome

E)n chromosomes

back 34

B

front 35

35)In alternation of generations, what is the diploid stage of a plant that follows fertilization called?

A)chiasmata

B)gametophyte

C)sporophyte

D)karyotype

E)spore

back 35

C

front 36

36)How are sister chromatids and homologous chromosomes different from each other?

A)They are not different. Homologous chromosomes and sister chromatids are both identical copies of each other.

B)Sister chromatids are only formed during mitosis. Homologous chromosomes are formed during meiosis

C)Homologous chromosomes are identical copies of each other. One sister chromatid comes from the father, and one comes from the mother.

D)Homologous chromosomes contain the same gene loci but may have different alleles of a particular gene. Sister chromatids are identical copies of each other produced during DNA replication.

E)Homologous chromosomes are closely associated with each other in both mitosis and meiosis. Sister chromatids are only associated with each other during mitosis.

back 36

D

front 37

37)During _____ sister chromatids separate.

A)interphase

B)prophase I

C)metaphase I

D)prophase II

E)anaphase II

back 37

E

front 38

38)During _____ a spindle forms in a haploid cell.
A) anaphase I
B) prophase II
C) metaphase I
D) metaphase II
E) telophase II and cytokinesis

back 38

B

front 39

39)During ____ the chromosomes finish their journey and two haploid daughter cells are produced, each chromosome still consists of two sister chromatids.

A) anaphase I
B) metaphase I
C) prophase I
D) telophase I and cytokinesis
E) metaphase II

back 39

D

front 40

40)At the end of _____ and cytokinesis, haploid cells contain chromosomes that each consist of two sister chromatids.
A) telophase
B) telophase I
C) metaphase II
D) telophase II
E) interphase

back 40

B

front 41

41)At the end of _____ and cytokinesis, haploid cells contain chromosomes that each consist of two sister chromatids.
A)telophase II
B)metaphase II
C)telophase I
D)telophase
E)interphase

back 41

C

front 42

42)Synapsis occurs during _____.
A)metaphase II
B)anaphase II
C)prophase I
D)prophase II
E)telophase I and cytogenesis

back 42

C

front 43

43)During _____ chromosomes align single file along the equator of a haploid cell.
A)metaphase II
B)anaphase I
C)telophase I and cytokinesis
D)metaphase I
E)prophase I

back 43

A

front 44

44)Homologous chromosomes migrate to opposite poles during _____.
A)metaphase II
B)anaphase I
C)metaphase I
D)telophase II and cytokinesis
E)prophase II

back 44

B

front 45

45)Mitosis results in the formation of how many cells; meiosis results in the formation of how many cells?

A)two diploid cells ... two diploid cells

B)four diploid cells ... four haploid cells

C)two diploid cells ... four haploid cells

D)four haploid cells ... two diploid cells

E)two diploid cells ... two haploid cells

back 45

C

front 46

46)Which of the following occurs during meiosis but not during mitosis?

A)Synapsis occurs.

B)A spindle apparatus forms.

C)Chromosomes align at the metaphase plate

D)Chromosomes condense

E)Chromosomes migrate to opposite poles

back 46

A

front 47

47)Which of these gametes contains one or more recombinant chromosomes?

A) A and B

B) B and C

C) A and D

D) D and E

E) A and C

back 47

B

front 48

48)A human cell containing 22 autosomes and a Y chromosome is
A) a sperm.
B) an egg.
C) a zygote.
D) a somatic cell of a male.
E) a somatic cell of a female.

back 48

A

front 49

49)Homologous chromosomes move toward opposite poles of a dividing cell during
A) mitosis
B) meiosis I
C) meiosis II
D) fertilization
E) binary fission

back 49

B

front 50

50)Meiosis II is similar to mitosis in that
A) sister chromatids separate during anaphase
B) DNA replicated before the division
C) the daughter cells are diploid
D) homologous chromosomes synapse
E) the chromosome number is reduced.

back 50

A

front 51

51)Look at the cell in the figure. Based on this figure, which of the following statements is true?

A)This cell is haploid.

B)This cell is diploid.

C)It is impossible to tell whether the cell is haploid or diploid.

back 51

B

front 52

52)Which life cycle stage is found in plants but not animals?

A)gamete

B)multicellular haploid

C)zygote

D)multicellular diploid

E)unicellular diploid

back 52

B

front 53

53)Why do some species employ both mitosis and meiosis, whereas other species use only mitosis?

A)A single-celled organism only needs mitosis.

B)They need meiosis if the cells are producing organs such as ovaries

C)They need only meiosis if they produce egg cells.

D)They need only mitosis to make large numbers of cells such as sperm.

E)They need both if they are producing animal gametes.

back 53

E

front 54

54) Nucleoli are present during _____.

A)metaphase

B)prophase

C)interphase

D)prometaphase

E)anaphase

back 54

C

front 55

55)During _____ both the contents of the nucleus and the cytoplasm are divided.

A)G2

B)the mitotic phase

C)mitosis

D)G1

E)S

back 55

B

front 56

56)During _____ the cell grows and replicates both its organelles and its chromosomes.

A)cytokinesis

B)interphase

C)mitosis

D)G1

E)S

back 56

B

front 57

57)Which of the following correctly matches a phase of the cell cycle with its description?

A)M: duplication of DNA

B)G1: follows cell division

C)G2: cell division

D)S: immediately precedes cell division

E)All of the above are correctly matched.

back 57

B

front 58

58)One difference between cancer cells and normal cells is that cancer cells

A)cannot function properly because they are affected by density-dependent

B)are arrested at the S phase of the cell cycle.

C)are always in the M phase of the cell cycle.

D)are unable to synthesize DNA.

E)continue to divide even when they are tightly packed together.

back 58

E

front 59

59)A particular cell has half as much DNA as some other cells in a mitotically active tissue. The cell in question is most likely in

A)metaphase.

B)anaphase.

C)G2

D)G1

E)prophase

back 59

D

front 60

60)The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

A)DNA synthesis

B)spindle formation

C)cleavage furrow formation and cytokinesis

D)spindle attachment to kinetochores

E)cell elongation during anaphase

back 60

c

front 61

61)Asexual reproduction _____.

A)produces offspring genetically identical to the parent

B)requires both meiosis and mitosis

C)is limited to plants

D)is limited to single-cell organisms

E)leads to a loss of genetic material

back 61

A

front 62

62)For what purpose(s) might a karyotype be prepared?

A)for prenatal screening, to determine if a fetus has the correct number of chromosomes

B)to determine whether a fetus is male or female

C)to detect the possible presence of chromosomal abnormalities such as deletions, inversions, or translocations

D)The first and second answers are correct

E)The first three answers are correct.

back 62

E

front 63

63)In alternation of generations, what is the diploid stage of a plant that follows fertilization called?

A) gametophyte
B) chiasmata
C) sporophyte
D) karyotype
E) spore

back 63

C

front 64

64)This chromosome has two chromatids, joined at the centromere. What process led to the formation of the two chromatids?

A)The two chromatids were formed by synapsis and the formation of a synaptonemal complex.

B)The two chromatids were formed by fertilization, bringing together maternal and paternal chromatids.

C)The two chromatids were formed by duplication of a chromosome.

back 64

C

front 65

65)Two sister chromatids are joined at the centromere prior to meiosis. Which statement is correct

A)These chromatids make up a diploid chromosome.

B) The cell that contains these sister chromatids must be haploid.

C)Barring mutation, the two sister chromatids must be identical

back 65

C

front 66

What is the best evidence telling you whether this cell is diploid or haploid?

A)The cell is haploid because the chromosomes are not found in pairs.

B)The cell is diploid because it contains two sets of chromosomes.

C)The cell is diploid because each chromosome consists of two chromatids

back 66

B

front 67

67)Identify all possible products of meiosis in plant and animal life cycles.

A)Gametes

B)Spores

C)Multicellular adult organisma

D) A AND B

back 67

D

front 68

81)What is crossing over?
A)-a direct consequence of the separation of sister chromatids
B)-also referred to as the "independent assortment of chromosomes"
C)-the movement of genetic material from one chromosome to a nonhomologous chromosome
D)-making an RNA copy of a DNA strand
E)-the exchange of homologous portions of nonsister chromatids

back 68

E

front 69

82)non-homologous chromosomes

A)

B)

C)

D)

E)

back 69

A

front 70

83) sister chromatids

A)B, G

B)C,F

C)A,B

D)F,C

E)E,A

back 70

A

front 71

84)homologous chromosomes

A)B, G

B)C,F

C)A,B

D)F,C

E)E,A

back 71

B

front 72

85) centromere

A)

B)

C)

D)

E)

back 72

D

front 73

86)nonsister chromatids

A)

B)

C)

D)

E)

back 73

E

front 74

87)Which of the following defines a genome?
A)-the complete set of an organism's polypeptides
B)-the complete set of an organism's genes
C)-a karyotype
D)-the complete set of a species' polypeptides
E)-representation of a complete set of a cell's polypeptides

back 74

B

front 75

88)Which of the following is true of a species that has a chromosome number of 2n = 16?
A)-During the S phase of the cell cycle there will be 32 separate chromosomes.
B)-A gamete from this species has four chromosomes.
C)-The species is diploid with 32 chromosomes per cell.
D)-The species has 16 sets of chromosomes per cell.
E)-Each cell has eight homologous pairs.

back 75

E

front 76

89)Assume that an organism exists in which crossing over does not occur, but that all other processes associated with meiosis occur normally. Consider how the absence of crossing over would affect the outcome of meiosis.

If crossing over did not occur, which of the following statements about meiosis would be true? Select all that apply.

A)The two sister chromatids of each replicated chromosome would no longer be identical.

B)Independent assortment of chromosomes would not occur.

C)There would be less genetic variation among gametes.

D)The two daughter cells produced in meiosis I would be identical.

back 76

C

front 77

90)The shuffling of chromosomes that occurs during both fertilization and _____ can lead to genetic variation.

A)natural selection

B)mutation

C)meiosis

D)genetic drift

E)mitosis

back 77

C

front 78

91)Heritable variation is required for which of the following?

A)mitosis
B)evolution
C)the production of a clone
D)meiosis
E)asexual reproduction

back 78

b

front 79

92)Homologous chromosomes move toward opposite poles of a dividing cell during
A)meiosis I.
B)fertilization.
C)meiosis II.
D)mitosis.
E)binary fission.

back 79

A

front 80

93)Meiosis II is similar to mitosis in that
A)the chromosome number is reduced.
B)the daughter cells are diploid.
C)homologous chromosomes synapse.
D)sister chromatids separate during anaphase.
E)DNA replicates before the division.

back 80

D

front 81

94)We can see that the chromosomes are duplicated and lined up by homologous pair.

A)the start of mitosis

B)just before mitosis

C)just before mitosis

D)the start of meiosis II

E)the start of meiosis I

back 81

E

front 82

95)Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and, therefore, can be assayed to track their incorporation. In a set of experiments, a studentfaculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times.

The research team used their experiments to study the incorporation of labeled nucleotides into a culture of lymphocytes and found that the lymphocytes incorporated the labeled nucleotide at a significantly higher level after a pathogen was introduced into the culture. They concluded that _____.

A)infection causes cell cultures in general to reproduce more rapidly

B)infection causes lymphocytes to divide more rapidly

C)infection causes lymphocyte cultures to skip some parts of the cell cycle

D)the presence of the pathogen made the experiments too contaminated to trust the results

back 82

B

front 83

96)In the figure above, which number represents DNA synthesis?

A)I

B)II

C)III

D)IV

back 83

B

front 84

97)In the figure above, at which of the numbered regions would you expect to find cells at metaphase
a)I or V
b)II only
c)III only
d)IV only

back 84

C

front 85

98)The unlettered circle at the top of the figure shows a diploid nucleus with four chromosomes that have not yet replicated. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is black, and the other is gray. The circles labeled A to E show various combinations of these chromosomes.

25) What is the correct chromosomal condition at prometaphase of mitosis?

A) B

B) C

C) D

D) E

back 85

A

front 86

99)The unlettered circle at the top of the figure shows a diploid nucleus with four chromosomes that have not yet replicated. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is black, and the other is gray. The circles labeled A to E show various combinations of these chromosomes.

26) What is the correct chromosomal condition for one daughter nucleus at telophase of mitosis?

A) B

B) C

C) D

D) E

back 86

D

front 87

100)If the cell whose nuclear material is shown in the accompanying figure continues toward completion of mitosis, which of the following events would occur next?

A) spindle fiber formation

B) nuclear envelope breakdown

C) formation of telophase nuclei

D) synthesis of chromatids

back 87

C

front 88

88)A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus. How many picograms would be found at the end of S and the end of G2?

A) 8; 8

B) 8; 16

C) 16; 8

D) 16; 16

back 88

D

front 89

89)Metaphase is characterized by _____.

A) aligning of chromosomes on the equator

B) splitting of the centromeres

C) cytokinesis

D) separation of sister chromatids

back 89

A

front 90

90)If there are 20 centromeres in a cell at anaphase, how many chromosomes are there in each daughter cell following cytokinesis?

A) 10

B) 20

C) 40

D) 80

back 90

A

front 91

91)Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol disrupts microtubule formation. Surprisingly, this stops mitosis. Specifically, Taxol must affect _____.

A) the structure of the mitotic spindle

B) anaphase

C) formation of the centrioles

D) chromatid assembly

back 91

A

front 92

92)Which of the following are primarily responsible for cytokinesis in plant cells but not in animal cells?

A) kinetochores

B) Golgi-derived vesicles

C) actin and myosin

D) centrioles and centromeres

back 92

B

front 93

93)Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA?

A) G1

B) S

C) G2

D) M

back 93

C