Renal Function

Helpfulness: 0
Set Details Share
created 2 years ago by Pmborton
13 views
show moreless
Page to share:
Embed this setcancel
COPY
code changes based on your size selection
Size:
X
Show:
1

diet, physical activity, and health

factors that vary normal ranges as urine volume and solute composition

2

osmolality (osmoses per kilogram) (Os/kg)

affected by solute number, not size or weight; determined in distal and collecting tubules when ADH is present

3

275-300 mOsm/kg

normal range of serum osmolality

4

275-900 mOsm/kg

normal range of urine osmolality

5

1.0-3.0

normal urine to serum ratio

6

specific gravity

comparison of density of urine to that of water; depends on number of particles and mass

7

1.002-1.035

normal urine specific gravity range

8

>1.010

specific gravity of concentrated urine

9

<1.010

specific gravity of diluted urine

10

>1.050

specific gravity not physiologically possible occurring due to contrast media

11

polyuria

issues leading to greater than 3L of urine per day;

12

water diuresis <200 mOsm/kg

ADH secretion inadequate or ineffective receptors leading to polyuria

13

solute diuresis >300 mOsm/kg

no common feature, but involve glucose, urea, or sodium leading to polyuria

14

oliguria

less than 400 mL/day of urine due to urinary obstruction, tubular dysfunction, and fluid loss

15

anuria

absence or cessation of urine excretion due to progressive renal disease or renal failure

16

osmolality

more accurate reflection of kidney's concentrating ability, since only solute number affects it

17

urea, chloride, and sodium

three most prevalent solutes

18

neurogenic diabetes insipidus

diabetes insipidus caused by defective ADH production

19

nephrogenic diabetes insipidus

diabetes insipidus caused by lack of renal response to ADH

20

renal clearance tests to assess glomerular filtration rate

volume of plasma in mL that is completely cleared of a substance per unit of time

21

C(mL/min)= U (mg/dL) x V (Ml/min) /P (mg/dL

GFR calculation C = calculated renal clearance P = plasma concentration U = urine concentration V = volume of urine

22

creatinine clearance

calculated measurement of the rate at which creatinine is removed from the plasma by the kidneys; used to measure renal function (GFR)

23

creatinine

an endogenous substance not affected by diet; filtered by glomerulus but not secreted or absorbed by renal tubules

24

24 hour urine collection

specimen for creatinine clearance

25

clearance = U x V / P x 1440

creatinine clearance

26

90-130 mL/min

basic creatinine clearance reference range

27

albuminuria

appears early in diabetic nephropathy; early detection of low levels signals need for additional testing and aggressive intervention; linked to hyperglycemia