Activity 8: The Pancreas and Examining the Histology of the Pancreas

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1

The pancreas is what type of gland?

Mixed gland

2

The pancreas is found across the posterior or anterior abdominal wall?

Posterior abdominal wall

3

The pancreas extends from what organ (i.e. on the left side) to what region of the small intestine?

Extends from the spleen to the duodenum of the small intestine

4

As a mixed gland, the pancreas has what 2 functions? (Hint: Think "exo" and "endo")

1. Endocrine function

2. Exocrine function

5

Through its endocrine function, the pancreas produces what 2 hormones?

1. Insulin

2. Glucagon

6

The exocrine function of the pancreas is produced by by which cell type in the pancreas?

By the pancreatic acinar cells

7

The exocrine function of the pancreas produces which type of enzymes?

Hydrolytic enzymes

8

The hydrolytic enzymes produced by the exocrine function of the pancreas are secreted into which region of the small intestine through which duct?

Secreted into the duodenum of the small intestine through the pancreatic duct

9

Describe the pH of pancreatic juice.

Very alkaline

10

Pancreatic juice has a high concentration of what specific ion?

Bicarbonate ion (HCO3 -)

11

What is the function of the high concentration of bicarbonate ion in pancreatic juice?

Neutralizes the acidic chyme entering the duodenum from the stomach

12

The high concentration of bicarbonate ion in pancreatic juice enables which 2 groups of enzymes to operate and why?

Enables the pancreatic and intestinal enzymes to operate at their optimal pH, which is slightly alkaline

13

Pancreatic tissue is composed of which 2 clusters of cells?

1. Pancreatic islets

2. Acinar cells

14

Which group of cells is involved in the endocrine function of the pancreas?

The pancreatic islets

15

The pancreatic islets are further composed of which 2 specific cell types?

1. Alpha cells

2. Beta cells

16

1. The alpha cells stain what color?

2. The beta cells stain what range of colors?

1. Red

2. Lavender-blue

17

Alpha cells of the pancreatic islets produce which hormone?

Glucagon

18

Beta cells of the pancreatic islets produce which hormone?

Insulin

19

Which group of cells is involved in the exocrine function of the pancreas and produces the hydrolytic enzymes?

The acinar cells

20

The hydrolytic enzymes produced by the acinar cells are important for what process in the duodenum?

Digestion

21

Which group of cells forms the major portion of the pancreatic tissue?

Acinar cells

22
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