Activity 9: Measuring Plasma Cholesterol Concentration

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1

What is atherosclerosis?

The disease in which the body's blood vessels become blocked by plaques

2

What condition can plaques contribute to?

Hypertensive heart disease

3

Plaques also serve as the starting points for what the formation of what?

Blood clots

4

Why are blood clots dangerous to the circulatory pathway?

They can break away and block smaller vessels downstream, causing heart attacks or strokes.

5

What is a major component of the smooth muscle plaques formed during atherosclerosis?

Cholesterol

6

What is a normal range for total plasma cholesterol in adult?

130-200 mg per 100 ml of plasma

7

What protein carries "good" cholesterol and what protein carries "bad" cholesterol?

HDL (high density lipoprotein): good cholesterol, LDL (low density lipoprotein): bad cholesterol

8

Why does HDL carry "good" cholesterol and LDL carry "bad" cholesterol?

Cholesterol bound to HDLs is destined to be degraded by the liver and eliminated from the body, whereas cholesterol binding to LDLs travel instead to the tissue walls.

9

How can the plasma cholesterol concentration level be misleading? (Hint: HDL and LDL levels)

A person can have a high cholesterol count and be alright if his concentration of HDL is high and his LDL concentration is low.