Activity 7: Blood Typing
What is blood typing?
System of blood classification
The factors routinely typed for are antigens of what 4 blood groups?
Blood typing is based on the presence of what and on where?
Presence of specific glycoproteins on the outer surface of the RBC plasma membrane
The glycoproteins used for blood typing are called what specifically?
How are antigens/agglutinogens determined?
For ABO blood groups, their antigens are accompanied by what other specific plasma proteins?
1. What is the function of antibodies/agglutinins?
2. What if the donor blood type doesn't match?
1. Act against RBCs carrying antigens that are not present on the person's own RBCs
2. The recipient's antibodies react with the donor's blood antigens, causing the RBCs to clump, agglutinate, and hemolyze.
Describe individuals who carry the Rh antigen.
Describe individuals who do not carry the Rh antigen.
How are ABO and Rh blood groups different?
Rh positive or Rh negative blood do not carry preformed anti-Rh antibodies
Rh negative blood can be given to what 2 blood types?
1. Rh negative blood
2. Rh positive blood
Rh positive blood can be given to only what blood type?
1. Rh positive
Why can't Rh positive blood be given to Rh negative blood when Rh negative blood can be given to Rh positive blood?
Rh negative persons who receive Rh positive blood start to produce anti-Rh antibodies. On subsequent exposures to Rh positive blood, you get hemolysis of the donor blood cells.