Activity 6: Determining Coagulation Time
The Ivy method results in bleeding that lasts for how long?
The duke method results in bleeding that lasts for how long?
What is the bleeding time?
The amount of time the bleeding lasts
The bleeding time indicates what ability?
The ability of platelets to stop bleeding in capillaries and small vessels
Prolonged bleeding time is most often associated with what 2 conditions involving platelets?
1. Deficient platelets
2. Abnormal platelets
Describe blood clotting or coagulation in regard to blood loss.
Minimizes blood loss when blood vessels are ruptured
Describe hemostasis or the blood clotting process in 5 steps.
1. Injured tissues and platelets release tissue factor (TF) and PF 3, triggering the clotting cascade
2. TF and PF3 interact with other blood protein clotting factors and calcium to form prothrombin activator
3. Prothrombin activator converts prothrombin to thrombin
4. Thrombin polymerizes with soluable fibrinogen proteins into insoluable fibrin
5. The fibrin forms strands that traps the RBCs and forms clots