Activity 3: Differential White and Red Blood Cell Counts
What does a total WBC count determine?
The total number of WBCs per unit volume of blood
What does a total RBC count determine?
The total number of RBCs per unit volume of blood
What is leukocytosis?
An abnormally high WBC count
What 5 conditions may leukocytosis indicate?
1. Bacterial infection
2. Viral infection
3. Metabolic disease
5. Poisoning by drugs/chemicals
What is leukopenia?
A decrease in the white cell number below 4000 per cubic millimeter of blood
What 5 conditions may leukopenia indicate?
1. Infectious hepatitis
2. Infectious cirrhosis
4. Excessive antibiotic therapy
5. Excessive X-ray therapy
Leukemia is a disorder of what tissues?
A disorder of the of the lymphoid tissues
Leukemia is characterized by uncontrolled proliferation of what cells and the reduction in what 2 cells?
Uncontrolled proliferation of abnormal WBCs and reduction in the number of RBCs and platelets
What 2 counts can detect leukemia?
1. Total WBC count
2. Differential WBC count
What is polycythemia?
Increase in the number of RBCs
Polychythemia may result from what 2 conditions?
1. Bone marrow cancer
2. Living at high altitudes where less oxygen is available
A decrease in RBCs result in what medical condition?
Describe anemia in regard to oxygen-carrying capacity.
Anemia indicates decreased oxygen-carrying capacity of blood
The decreased oxygen-carrying capacity of blood, referred to as anemia, can arise due to what 2 causes?
1. Decrease in RBC number
2. Decreased hemoglobin content of RBCs
RBCs may suddenly decrease in number due to what 2 conditions?
2. Conditions destroying RBCs or hindering RBC production
How is a differential white blood cell count performed?
Counting 100 WBCs and classifying them based on type
Why is a differential white blood cell count important in regard to abnormality?
Abnormality in percentages of WBC types may indicate a problem and the source of pathology