antibiotics and modes of action

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Microbiology
Chapter 20
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1

metronidazole

interfere with anaerobic metabolism

antiprotozoan drug

2

ribavirin

inhibits DNA or RNA synthesis

antiviral drug

3

cloxacillin

interferes with last stage of bacterial cell wall synthesis

semisynthetic penicillin

4

vancomycin

inhibits second stage of cell wall biosynthesis

polypeptide antibiotic

5

penicillin V

taken orally. inhibits cell wall synthesis

against gram positive bacteria

natural penicillin

6

fluconazole

inhibits fungal activity

7

ethambutol

inhibits incorporation of mycolic acid into cell wall

antimycobacterial antibiotic

8

oxacillin

cell wall synthesis

semisynthetic penicillin

9

azithromycin

protein synthesis inhibitor

macrolides

10

tetracycline

protein synthesis inhibitor

broad spectrum

11

aminoglycoside

protein synthesis inhibitor

12

doxycycline

acne treatment

protein synthesis inhibitor

13

antiviral

cell wall synthesis

14

neomycin

protein synthesis iinhibitor

aminoglycoside

15

acyclovir

DNA or RNA synthesis inhibitor

16

penicillin G

requires injection

natural penicillin

cell wall synthesis inhibitor

17

bacitracin

polypeptide antibiotic

against gram positive bacteria

cell wall synthesis inhibitor

18

isoniazid

inhibits synthesis of mycolic acid

antimycobacterial antibiotic

cell wall synthesis inhibitor

19

chloramphenicol

inhibitor of protein synthesis

broad spectrum

20

polymyxin B

injury to plasma membrane

21

rifampin

inhibitor of nucleic acid synthesis

inhibits synthesis of mRNA

22

ciprofloxacin

inhibits DNA synthesis

nuceic acid synthesis inhibitor

quinolones and fluoroquinolones

23

chloroquine

inhibits DNA synthesis

antiprotozoan drug

24

niclosamide

prevents ATP generation in mitochondria

25

mebendazole, albendazole

inhibits absorption of nutrients