Bio 101 - Chapter 6
Metabolic pathway
a specific molecule is altered in a series of defined steps, resulting in a product
Catabolic pathways
release energy by degrating complex molecules to simple
Anabolic pathways
require energy to build things
1st law of thermodynamics
the amount of energy in the universe is constant. Matter can't be created nor destroyed
2nd law of thermodynamics
every energy transfer increases entropy in the universe. Enthropy or randomness. Less organized
Thermodynamics
heat and evergy
Catabolic process
cell releases free energy in a series of reactions
Anabolic process
cell requires free energy by pumping in
Exergonic
release of energy
Endergonic
requirement of energy
Catalyst
a chemical agent that speeds up a reaction
Enzyme
a catalyst. Ex: Hemoglobin
Activation energy
the initial investment of energy for a starting reaction
Transition state
free energy at it's highest points which makes molecules more unstable for the reaction
Induced fit
enzyme changes shape to fit substrate
Cofactors
non-protein helpers for many enzymes. They bind perminately or reversibly to the enzyme. Ex: Copper, Zinc and Iron
Coenzymes
Organic cofactors. Ex: Vitamins
Competitive inhibitors
reduce the productivity of enzymes by blocking substrates from entering active sites. Don't react with the enzyme
Noncompetitive inhibitors
do not bind to the active site of the enzyme.
Multimeric enzyme
enzyme with quatenery structure
Allosteric regulation
other site activator or inhibitor. There is a balance between the 2. Noncompetitive
Allosteric activator
stabilizes active form of enzyme (turns it on)
Allosteric inhibitor
stabilizes inactive form of enzyme (turn off)
Coopertivity
takes the inactive enzyme that binds with a substrate to make it active. Ex: Hemoglobin (it gives more oxygen to harder working muscles)
Threonine
amino acid that binds to an enzyme to make an end product isoleucine (on switch)
Isoleucine
amino acid that prevents threonine from binding to the enzyme (off switch)
Allosteric enzyme
the first enzyme that threonine binds to to start the reaction