Exam 3

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created 4 years ago by crwiley
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Microbiology
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Chapter 17, 18 , 19, 20, 21, 22, 23, 24, 25, 26 and 27
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1

Antibody

Proteinaceous substance made by specialized lymphocytes in response to antigen.

2

Antigen

Organisms of substances that provoke immune systems to produce antibodies or cell mediated immunity

3

Humoral Immune System

Production of antibody with help of blymphocytes

(antibody producing system

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Cell Mediated Immune System

antigens T Lymphocytes (immune system divided into 2 parts)

5

B Lymphocytes

Plasma cells - Antibody

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T Lymphocytes

Cytoxic or killer cells

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Antigenic determinant

will have capability of being antibody

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Antibody Structures

  1. 5 types of C Regions
  2. H Chains
  3. 2 types of L Chains
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5 Classes

  1. IgG
  2. IgD
  3. IgE
  4. IgA - Dimer
  5. IgM - Pentamer
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Blood Grouping

ABO

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IgA

...

12

IgD

...

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IgE

...

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Antigen presenting cells

activated macrophages

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Apoptosis

Programmed cell death

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Immunological Memory

Booster shots in vaccination

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Memory cells

live long time and get activated when exposed to same antigen later in life

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T lymphocytes

Helper cells

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Cytotoxic cells

CD8 (killers)

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Inactivated vaccines

Rabies, Polio, Influenza, salmonella

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Live (attenuated) vaccine

Polio, Yellow Fever, Measles, Mumps, Rubella

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Limitations

takes 2 weeks to build/awake antibodies

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Serologic Tests

Mediated by antibody

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Neutralization Reactions

Serum virus neutralization test

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Enzyme linked immunosorbent assay

can run persons serum cell sample all at once

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harmful effects

allergies, transplant rejection

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Type I (Anaphylaxis) Reactions

Most common allergy

28

Adrenaline (epinephrine)

foods fish, milk, dust mite feces

29

Harmful effects

allergies, transplant rejection