Chapter 19 Microbial Diseases of the Skin and Wounds

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Microbiology
Chapter 19
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1

Folliculitis

Signs and symptoms

  • Infection of hair follicle
  • Often called a pimple
  • Called a sty when occurs at eyelid base
  • Spread of infection into surrounding tissues can produce furuncles
  • Carbuncles occur when multiple furuncles grow together
2

Folliculitis

Pathogen and virulence factors

  • Staphylococcus
  • Facultatively anaerobic, Gram-positive bacteria
  • Cocci arranged in clusters
  • Tolerant of salt and desiccation
  • Two species found on skin:

Staphylococcus epidermis

Staphylococcus aureus

3

Folliculitis

  1. Diagnosis
  2. Treatment
  3. Prevention
  1. Isolation of Gram-positive bacteria in grapelike clusters from pus
  2. Dicloxacillin and Vancomycin (for resistant strains)
  3. Hand antisepsis and proper hospital procedures to minimize MRSA
4

Staphylococcal Scalded Skin Syndrome

Signs and symptoms

  • Skin becomes red, wrinkled, and forms blisters
  • Outer epidermis peels off in sheets
5

Staphylococcal Scalded Skin Syndrome

Pathogen and virulence factors

  • Some Staphylococcus aureus strains
  • One or two different exfoliative toxins cause SSSS
6

Staphylococcal Scalded Skin Syndrome

Pathogenesis

  • No scarring because dermis unaffected
  • Death is rare, but may be due to secondary infections
7

Staphylococcal Scalded Skin Syndrome

Epidemiologh

  • Disease occurs primarily in infants
  • Transmitted by person-to-person spread of bacteria
8

Staphylococcal Scalded Skin Syndrome

  1. Diagnosis
  2. Treatment
  3. Prevention
  1. Diagnosed by characteristic sloughing of skin
  2. Antimicrobial drugs
  3. Widespread presence of S. aureus makes prevention difficult