Chapter 19 Microbial Diseases of the Skin and Wounds
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1
Folliculitis
Signs and symptoms
- Infection of hair follicle
- Often called a pimple
- Called a sty when occurs at eyelid base
- Spread of infection into surrounding tissues can produce furuncles
- Carbuncles occur when multiple furuncles grow together
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Folliculitis
Pathogen and virulence factors
- Staphylococcus
- Facultatively anaerobic, Gram-positive bacteria
- Cocci arranged in clusters
- Tolerant of salt and desiccation
- Two species found on skin:
Staphylococcus epidermis
Staphylococcus aureus
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Folliculitis
- Diagnosis
- Treatment
- Prevention
- Isolation of Gram-positive bacteria in grapelike clusters from pus
- Dicloxacillin and Vancomycin (for resistant strains)
- Hand antisepsis and proper hospital procedures to minimize MRSA
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Staphylococcal Scalded Skin Syndrome
Signs and symptoms
- Skin becomes red, wrinkled, and forms blisters
- Outer epidermis peels off in sheets
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Staphylococcal Scalded Skin Syndrome
Pathogen and virulence factors
- Some Staphylococcus aureus strains
- One or two different exfoliative toxins cause SSSS
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Staphylococcal Scalded Skin Syndrome
Pathogenesis
- No scarring because dermis unaffected
- Death is rare, but may be due to secondary infections
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Staphylococcal Scalded Skin Syndrome
Epidemiologh
- Disease occurs primarily in infants
- Transmitted by person-to-person spread of bacteria
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Staphylococcal Scalded Skin Syndrome
- Diagnosis
- Treatment
- Prevention
- Diagnosed by characteristic sloughing of skin
- Antimicrobial drugs
- Widespread presence of S. aureus makes prevention difficult