Function of bone:
For the body and soft organs
What is Support?
Function of bone:
For brain, spinal cord, and vital organs
What is protection?
Function of bone:
- Levers for muscle action via tendons.
- Ligaments prevent excessive movement
What is movement?
Function of bone:
Minerals (calcium and phosphorus) in bone matrix and triglycerides (fat for energy) in bone cavitites (yellow marrow)
What is storage?
Function of the bone:
- (hematopoiesis) in marrow cavities (red marrow)
What is blood cell formation?
What are the main components of skeletal system?
Bone, Cartilage, Tendons, and ligaments
What are the 3 types of cartilage?
Elastic, Fibrocartliage, Hyaline
Contain no blood vessels or nerves
What is cartilage?
- Cells: chondroblasts : produce matrix
What is Skeletal Cartilage?
- Chondrocytes: reside in lacunae
What is Skeletal Cartilage?
What is the matrix of skeletal cartilage?
collagen fibers and proteoglycans
Skeletal cartilage
covers the outer surface of cartilage-> contains blood vessels for nutrient delivery to cartilage
What is Perichondrium membrane?
hyaline cartilage covering bones at joints has no perichondrium
What is Articular cartilage?
- respiratory cartilage (trachea and bronchi) and nasal cartilage
- Provide support, flexibility, and resilience
- Most abundant type
- articular cartilage
- costal cartilages (ribs)
What is Hyaline Cartilage?
- Collagen fibers—have great tensile strength
- Pubic symphysis , menisci of knee, intervertebral discs
What is fibrocartilage?
Growth of cartilage:
Appositional
- Cells secrete matrix against the external face of existing cartilage
Growth of cartilage:
-Chondrocytes divide and secrete new matrix, expanding cartilage from within.
What is Interstitial?
Calcification of cartilage
-occurs during normal bone growth and old age
bind bone to bone
What are Ligaments?
bind muscle to bone
What are tendons?
Bone histology
Bone is connective tissue thus made of
CELLS
Bone histology
- stuff between cells, secreted by cells
What is matrix
What are the components of matrix?
Fibers and ground substance
The remodeling of bone tissue is a function of
what is osteoblast and osteoclast activity?
Compared to other tissues, normal bone growth requires higher amounts of _____, _____, and _____ in the diet.
calcium, phosphate, and vitamin D
The spaces between developing skull bones that have not ossified are called
what is fontanels?
In endochondral ossification, chondroblasts produce a _________ cartilage model that has the approximate shape of the bone to be formed.
hyaline
In _________ growth of cartilage, chondrocytes within the tissue divide and add more matrix between the existing cells.
interstitial
These house the blood vessels that carry blood from the medullary cavity and periosteum to the osteon and run perpendicular to the long axis of the bone.
What are perforating canals?
In __________ growth of cartilage, chondroblasts in the perichondrium add new cartilage to the outside edge of the existing cartilage.
appositional
Which matrix molecules in cartilage tends to trap large quantities of water?
proteoglycan
Articular cartilage covers the ends of long bones. Consists of specialized cells that called chondroblasts that produce new cartilage matrix surrounding themselves. Become chondrocytes when surrounded trapped in lacunae ; serves as a precursor for the formation of long bones in the body
What is Hyaline Cartilage
Growth of cartilage in which chondroblasts in the perichondrium add new cartilage to the outside edge of existing cartilage
What is Appositional growth
Chondrocytes within the tissue divide and add more matrix between cells of cartilage
What is Interstitial growth
Produce collagen and proteoglcans; release matrix vesicles, bone deposition, bone formation
What is Osteoblast?
Formation of bone by osteoblats; occurs by appositional growth
What is Ossification (osteogenesis)
has fibers that are randomly arranged in many directions; first to form during fetal development or during repair of fracture; remodeled into lamellar bone
What is Woven bone?
mature bone that is organized into thin sheets or layers; fibers are parallel to one another in one lamella but at an angle to the fibers in an adjacent lamellae
Lamellar bone
When blood calcium levels are low
ostoclast activity increases.
When blood calcium levels are too low, osteoclast activity increases.
What is calcium homeostasis
Ligaments attach
bone to bone
Collagen and calcium hydroxyapatite are the primary constituents of
What is bone matrix?
vitamin D is important because
it absorbs calcium
small, smooth surface of a bone where articulation occurs
what is facet
The connective tissue sheath of cartilage is called the
What is perichondrium
When the epiphyseal plate is replaced by bone,
bones have reached their adult length
Calcium is found in crystals called
what are hydroxyapatite?
are the basic units in compact bone tissue.
What is Haversian systems or osteons?