Microbiology L9

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created 6 years ago by kelliebob
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updated 6 years ago by kelliebob
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1

Yeast

unicellular organisms that reproduce asexually via budding

2

Mold

unicellular organisms that grow in slender thread like strands. Reproduce sexually & asexually

3

Pathogenic Fungi

dermatomycoses

systemic diseases can be caused by fungi and affect internal organs

4

Dermatomycosis

  • ringworm, athlete’s foot, tinea, and dermatophytosis
  • Genera that typically cause these infections are Trichophyton, Microsporum, and Epidermophyton
5

Coccidiodes immitis

  • causes Coccidioidomycosis and is found in soil
  • valley fever or desert rheumatism
  • primary form is lung nodule, progressive spread to almost any tissue or organ
6

Histoplasma capsulatum

  • causes histoplasmosis
    • primary: lungs
    • progressive or disseminated: mouth, throat, liver, spleen, lymph
  • dimorphic: grows as yeast (37C) or mold (25C)
  • found in soil, bird, or bat droppings
7

Candida albicans

  • causes Candidiasis (Monila)
  • found in normal oral flora (thrush)
  • starts in mouth, disseminates to other areas like lungs (focal lesions)
  • can cause genital yeast infections in women
8

Cryptococcus neoformans

  • cryptococcus- disease of lungs and then nervous system (meningitis)
  • encapsulated with polysaccharide capsule to help with virulence and anti-phagocytic properties
  • Type A&D most common in immunosuppressed hosts (90%)
  • found in soil/ pigeon droppings & inhaled
9

Aspergillus species

  • Aspergillosis
  • affects lungs of animals & man
  • found in decaying vegetation, spores cause allergy symptoms. progressive infection in weak hosts (similar to TB)
10

Blastomyces dermatidis

  • blastomycosis- systemic lung infection by yeast
  • chronic cutaneous blastomycosis- skin lesions that ulcerate (milder version)
  • dimorphic pathogen- mold in environment, yeast in host tissue
  • disseminated into GUT, skin, liver, CNS, spleen, bone, lymph, heart, adrenals, GI, pancreas
11

Protozoa

eukaryotic single celled animals that may exist as free living organisms in the environment or associated with a living host as a parasite

12

Balantidium

  • diarrhea
  • parasite: ciliata
13

Leishmania Trypanosoma

  • Sleeping sickness
  • parasite: Mastigophera
14

Entamoeba histolytica

  • amebiasis (amebic dysentery)
  • enters via mouth as cyst from unsanitary food or water. Cysts burst and organisms feed on intestinal contents and tissue (trophozoites)
  • Parasite: Sarcodina (Amoeba)
15

Giardia lamblia

  • Giardiasis- gastrointestinal illness
    • foul, greasy stool, bloating, gas, weakness, cramps, weight loss
  • consumption of water contaminated with infected feces or person-to person
  • as few as 10 parasites can cause infection
16

Plasmodium malariae

  • malaria- anapheles mosquito
  • electively localized in erythrocytes of infected human host
    • asexual reproduction in erythrocytes, sexual repro in mosquito
  • parasite: Apicomplexa (Sporozoa)
17

Pneumocystis jiroveci:- (book says carinii)

  • pneumocystis carinii pneumonia (PCP)- life threatening lung disease
  • can infect other organs including skin
  • found in lungs but doesn’t affect healthy people
18

Toxoplasma gondii

  • toxoplasmosis
  • zoonosis for all animals but mainly cats, subphylum Sporozoa
  • transmitted to humans via mouth
  • affinity for eye & brain tissue