Microbiology L8

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created 6 years ago by kelliebob
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Rickettsia, Chlamydia, Viruses
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1

Rickettsia

  • obligate intracellular parasites of man & arthropod vector
  • no flagella, pili, or spores
2

Rickettsia prowazekii

  • Epidemic Typhus Fever (louse)
  • MOT: louse bite via infected person
3

Rickettsia typhi

  • ENdemic Typhus Fever (flea)
  • murine fever; more mild than epidemic
  • zoonotic, mice & rats.
  • MOT: flea from infected rodent to man
4

Rickettsia rickettsii

  • Rocky Mtn Spotted Fever
  • MOT: infected tick
  • flu, fever, light sensitivity, red-black rash on extremities
5

Rickettsia tsutsagumushi

  • Scrub Typhus Fever
  • MOT: mite
  • headache, chill, fever, rash called eschar
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Coxiella burnetii

  • Q Fever
  • inhalation or ingestion of raw milk, tick bite
  • resistance to heat & sunlight, v virulent
  • high fever mild rash
7

Chlamydia

  • mantle-like cell covering
  • reproduces in cytoplasm of host cell
8

Chlamydia trachomatis

  • Trachoma (inclusion conjunctivitis)
  • MOT: direct contact w/ contaminated object
  • Climatic bubo (clap)
  • STD, lesions, necrotic bubos
  • Urethritis
9

Chlamydia psittaci

  • Psittacosis (ornithosis/ Parrot Fever)
  • MOT: dried feces or feather dust
  • upper respiratory infection, headache, fever, cough
10

Viruses

  • smallest, simplest form of life
  • obligate intracellular parasites
  • use hot cell resources to synthesize new virus
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Dermotropic Diseases

  • Variola (smallpox)
  • Rubeola (measles)
  • Rubella (3 day/ German)
  • Varicella Zoster (chicken pox/ shingles)
  • Herpesvirus hominis (herpes 1- cold sore & 2- std)
  • Coxsackie (foot & mouth)
12

Pneumotropic Diseases

  • Influenza
  • Common cold (acute coryza)
13

Neurotropic Diseases

  • Rabies (hydrophobia)
  • Poliomyelitis
  • Viral encephalitis
14

Viscerotropic Diseases

  • Hepatitis
  • Infectious mononucleosis (epstein barr)
  • Cytomegalovirus
  • Epidemic parotitis (mumps)
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  • Immunotropic
  • Prions
  • HIV
  • Creutzfeldt- Jakob (spongiform encephalitis)