Anatomy Chapter 17 Blood Flashcards


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1

Neutrophils

- most numerous
- polymorphonuclear leukocytes (PMNs)
- fine granules take up both acidic and basic dyes
- give the cytoplasm a lilac color
- granules contain hydrolytic enzymes or defensins
- very phagocytic (bacteria slayers)

2

Eosinophils

- red-staning,bilobed nulcei
- red to crimisn coarse,lysosome-like granules
- digest parasitc worms that are to large to be phagocytizing
- modulators of the immune response-lessen the severity of allergic

3

Basophils

- rarest WBCs
- have U or S shaped nuclei
- large-purplish black granule contain histamine
- are funtionally similar to mast cells

4

Lymphocytes

- account fro 25%-45% of WBCs
- smallest leukocyte
- have large,dark-purple,circular nuclei with a thin rim of blue cytoplasm
- are found mostly enmeshed in lymphiod tissue
- there are two types of lymphocytes:T cells and B cells
-T cells function in the immune response
- B cells give rise to plasma cells, which produce antibodies

5

Monocytes

- account for 3-8& of leukocytes
- they are the largest leukocytes
- they have purple-staining, U-kidney shaped nuclei
- they leave the circulation,enter tissue,and differentitate into marophages

6

Name two stem cells,derived from a hemocytoblast,from which all bllod cells rise

- myeloid stem cells
- lymphiod stem cells (all blood cells arise)

7

What mineral is in the center of each molecule heme?

iron

8

Marcophage are produced by which leukocyte?

monocyte

9

Name a chemical released by basophils that initiates an inflammatory reaction.Also name the anticoagulant released by basophils.

(1)histamine
(2)heparin

10

What Vitamin is necessary for synthesis of four clottin factors produced by the liver?

Vitamin k

11

Where is the primary RBC "graveyard"

spleen

12

Leukemia

refers to a group of cancerous conditions of white bllod cells

13

What mineral deficiency reults in a hypochromic,microcytic anemia?

iron

14

Causes of sickle cell anemia and pernicious anemia

(1)caused by the abnormal hemoglobin
(2)is due to deficency of vitamin B12

15

Anemia

reduced oxgen-carrying ability of blood resultig from too few erthrocytes or abnormal hemoglobin

16

Leukocytosis

an increase in the number of leukocytes (white blood cells);usally the result of a microbiological attack on the body

17

Leukopenia

abnormally low white blood cell count

18

Thrombocytopenia

a reduction in the number of platelets circulating in the blood

19

Oxyhemoglobin

oxgen-bound form of hemoglobin

20

Hemostasis

stoppage of bleeding

21

Thrombus

a clot that develops and persists in an unbroken blood vessel

22

Diapedesis

passage of white blood cells though intact vessel walls into tissue

23

Postive Feedback Mechanism

feedback that tends to cause the level of a variable to change in the same direction as an inital change

24

erythropoietin

hormone that stimulates production of the red blood cells

25

polcythemia

an abnormal excess of erthrocytes that increase blood visosity

26

phlebotomy

the process of making and incision in a vein

27

petechiae

wide spread of hemorage, evidenced by many small purplish spots