Mitosis Flashcards


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created 8 years ago by karissa_boesch
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Interphase

-Not part of mitosis

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Three distinct periods of interphase

G1-The centrioles begin replicating
S- DNA is replicated
G2- Final preparations for mitosis are completes and centrioles finish replicating

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Prophase- Early prophase

-Chromatin condenses forming barlike chromosomes
-Each duplicated chromosome consists of two identical threads called sister chromatids, held together at the centromere
-As chromosomes appear, the nucleoli disappear, and the two centrosomes separate from one another
-Centrosomes allow for the growth of mitotic spindles
-Asters "stars" extend from the centrosome matrix

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Late prophase

-Nuclear envelope breaks up, allowing spindle to interact with the chromosomes
-Spindle fibers attach to kinetochores
-Kinetochores pull on chromosomes, pulling them further apart

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Metaphase

-Two centrosomes are at opposite poles of the cell
-The chromosomes align at the equator (metaphase plate)
-Enzymes act to separate the chromatids from each other

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Anaphase

-Shortest phase
-Each chromatid splits and each become its own chromosome
-The kinetochores pull each chromosome toward the pole it faces

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Telophase

-A new nuclear envelope forms around each chromatin mass
-Nucleoli reappear within the nuclei, and the spindle breaks down and disappears
-End of mitosis

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Cytokinesis

-A contractile ring of actin microfilaments forms the cleavage furrow and pinches the cell apart