Arthropod-Borne Diseases

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created 7 years ago by krsbai
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1

What Cell Shape does Rickettsia rickettsii "Rocky Mountain Spotted Fever have?

Bacillus

2

What Cell Shape does Borrelia burgdorferi "Lyme's Disease" have?

Spirochete

3

What is Rocky Mountain Spotted Fever's transmission Vector?

Tick or Transovarially

4

What is Lyme's Disease transmission vector?

Tick

5

What are the virulence's of RMSP?

Endotoxin
Reproduces intracellular

6

What are the virulence's of Lyme's Disease?

Organism persists in tissue

7

What are the symptoms of RMSF?

High fever, headache, muscle paint, maculopapular rash starts on extremities and moves on to trunk of body.

8

What are the symptoms of Lyme's Disease?

stage I: fever, headache, secondary rash,
stage II: nervous system problems, cardiovascular problems
stage III: Late generalized disease, arthritis symptoms, intellectual deterioration

9

How is RMSP diagnosed?

Weil-Felix test

10

Hos is Lyme's Disease diagnosed?

Blood test to screen for antibody production

11

Is there a vaccine available for RMSF?

There use to be for individuals at high risk but this is no longer available.

12

Is there a vaccine available for Lyme's Disease?

Not currently available for human's.
There is a dog vaccine.

13

What is the treatment for RMSF?

Tetracycline

14

What is the treatment for Lyme's Disease?

Tetracycline
Intravenous antibiotics necessary in advanced cases

15

Who discovered the bacteria that causes RMSF?

Howard Ricketts

16

What is an obligate intracellular parasite?

-cannot be grown on artificial media
-requires animal tissue cells

17

What is the size of the Rickettsia bacteria and can the bacteria be seen with a compound microscope?

smaller than most bacteria, 0.5 micrometers
Yes can still be seen with a compound microscope.

18

How is the tick affected by RMSP?

Not harmed by disease

19

What two ways can the tick become infected with RMSF bacteria?

feeding on infected animal
transovarian transmission (female tick)

20

What is transovarian transmission of bacteria in ticks?

infected female tick-infected tick eggs-infected baby ticks

21

Can both RMSF and Lyme's Disease be transmitted to ticks via transovarian transmission?

RMSF can be but Lyme's cannot

22

Where is the tick belt in the US?

Eastern US (PA, GA, NY, VA, KY, TN, NC, SC)

23

What is disseminated intravascular coagulation?

Endotoxin causes bleeding from blood vessels and along with blood clotting
(spread vessels clot)

24

What are the characteristics of a maculopapular rash?

pink, raised spots
or hemorrhagic reaction

25

Where does a maculopapular rash start in RMSF?

extremities

26

What immunity if any is generated after recovery of RMSF?

Immunity seems to be permanent after recovery

27

What is the Weil-felix test and what disease does it diagnose?

It is a blood test using blood serum to diagnose RMSF

28

What is a preventative therapy to prevent disease transmission from tick to human?

Tick removal within 4hrs

29

Where was Lyme's disease first discovered?

Lyme, Connecticut

30

Who discovered the tick vector for Lyme's Disease?

Willy Burgdorfer

31

How is the tick affected by Lyme's Disease?

Unharmed

32

What is the only way that a tick can become infected with Lyme's Disease?

after feeding on an infected animal

33

What is the average life span of a tick?

2yrs

34

In the clinical progression of Lyme's Disease, through how many stages can the disease progress?

3

35

If treated properly in stage I Lyme's disease, would you expect a patient to progress to stage II?

no

36

What is erythema migrans?

skin rash expanding round about 6 inches at tick bite

37

How long does the symptom erythema migrans last for Lyme's disease?

3-4wks

38

In stage II of Lyme's disease, what percentage of patients usually have neurological problems?

15%

39

What type of neurological problems might a patient experience in stage II of Lyme's disease?

facial paralysis, headaches, fatigue, peripheral neuritis

40

In stage II Lyme's disease what percentage of patients have cardiovascular problems?

8%

41

What is the most serious stage of Lyme's disease?

Stage III

42

What is the antibiotic usually used to treat RMSF or Lyme's disease?

Tetracycline

43

What month is/are Lyme's disease cases more prevalent?

June and July

44

What is the most common arthropod-borne disease in the US?

Lyme's Disease

45

Are animals or humans a natural host for both Lyme's and RMSF?

Animals are natural host
Humans are accidental host

46

What kind of rash do you get from Lyme's Disease?

bulls-eye rash

47

what are some examples of possible animal reservoirs for Lyme's disease?

brown deer mice, white-tail deer, possum, skunk, dog, human, bird, squirrel, cat

48

what type of tick is the vector for Lyme's disease?
and what does it look like

deer tick/black legged tick

49

what type of tick is the vector for RMSF? and what does it look like?

wood tick/dark brown legs

50

RMSF usually requires an arthropod vector. What are some of those?

tick, lice, mite, fleas