What Cell Shape does Rickettsia rickettsii "Rocky Mountain Spotted Fever have?
What Cell Shape does Borrelia burgdorferi "Lyme's Disease" have?
What is Rocky Mountain Spotted Fever's transmission Vector?
Tick or Transovarially
What is Lyme's Disease transmission vector?
What are the virulence's of RMSP?
What are the virulence's of Lyme's Disease?
Organism persists in tissue
What are the symptoms of RMSF?
High fever, headache, muscle paint, maculopapular rash starts on extremities and moves on to trunk of body.
What are the symptoms of Lyme's Disease?
stage I: fever, headache, secondary rash,
stage II: nervous system problems, cardiovascular problems
stage III: Late generalized disease, arthritis symptoms, intellectual deterioration
How is RMSP diagnosed?
Hos is Lyme's Disease diagnosed?
Blood test to screen for antibody production
Is there a vaccine available for RMSF?
There use to be for individuals at high risk but this is no longer available.
Is there a vaccine available for Lyme's Disease?
Not currently available for human's.
There is a dog vaccine.
What is the treatment for RMSF?
What is the treatment for Lyme's Disease?
Intravenous antibiotics necessary in advanced cases
Who discovered the bacteria that causes RMSF?
What is an obligate intracellular parasite?
-cannot be grown on artificial media
-requires animal tissue cells
What is the size of the Rickettsia bacteria and can the bacteria be seen with a compound microscope?
smaller than most bacteria, 0.5 micrometers
Yes can still be seen with a compound microscope.
How is the tick affected by RMSP?
Not harmed by disease
What two ways can the tick become infected with RMSF bacteria?
feeding on infected animal
transovarian transmission (female tick)
What is transovarian transmission of bacteria in ticks?
infected female tick-infected tick eggs-infected baby ticks
Can both RMSF and Lyme's Disease be transmitted to ticks via transovarian transmission?
RMSF can be but Lyme's cannot
Where is the tick belt in the US?
Eastern US (PA, GA, NY, VA, KY, TN, NC, SC)
What is disseminated intravascular coagulation?
Endotoxin causes bleeding from blood vessels and along with blood clotting
(spread vessels clot)
What are the characteristics of a maculopapular rash?
pink, raised spots
or hemorrhagic reaction
Where does a maculopapular rash start in RMSF?
What immunity if any is generated after recovery of RMSF?
Immunity seems to be permanent after recovery
What is the Weil-felix test and what disease does it diagnose?
It is a blood test using blood serum to diagnose RMSF
What is a preventative therapy to prevent disease transmission from tick to human?
Tick removal within 4hrs
Where was Lyme's disease first discovered?
Who discovered the tick vector for Lyme's Disease?
How is the tick affected by Lyme's Disease?
What is the only way that a tick can become infected with Lyme's Disease?
after feeding on an infected animal
What is the average life span of a tick?
In the clinical progression of Lyme's Disease, through how many stages can the disease progress?
If treated properly in stage I Lyme's disease, would you expect a patient to progress to stage II?
What is erythema migrans?
skin rash expanding round about 6 inches at tick bite
How long does the symptom erythema migrans last for Lyme's disease?
In stage II of Lyme's disease, what percentage of patients usually have neurological problems?
What type of neurological problems might a patient experience in stage II of Lyme's disease?
facial paralysis, headaches, fatigue, peripheral neuritis
In stage II Lyme's disease what percentage of patients have cardiovascular problems?
What is the most serious stage of Lyme's disease?
What is the antibiotic usually used to treat RMSF or Lyme's disease?
What month is/are Lyme's disease cases more prevalent?
June and July
What is the most common arthropod-borne disease in the US?
Are animals or humans a natural host for both Lyme's and RMSF?
Animals are natural host
Humans are accidental host
What kind of rash do you get from Lyme's Disease?
what are some examples of possible animal reservoirs for Lyme's disease?
brown deer mice, white-tail deer, possum, skunk, dog, human, bird, squirrel, cat
what type of tick is the vector for Lyme's disease?
and what does it look like
deer tick/black legged tick
what type of tick is the vector for RMSF? and what does it look like?
wood tick/dark brown legs
RMSF usually requires an arthropod vector. What are some of those?
tick, lice, mite, fleas