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Lecture 1 part 2 Blood
updated 7 years ago by dadchaneefau
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what consist of 3 interrelated components in the CV system?

1. Blood
2. Heart
3. Blood vessels


what concern about Blood?

1. Hematology
2. Homeostasis which contributes by blood


What is Hematology?

The study of blood, Blood forming tissues, and the disorders associated with them


How blood contributes to Homeostasis?

1. TRANSPOTING respiratory gasses, nutrients, and hormones to and from your body's cells.
2. Helping to REGULATE body PH and temperature.
3. Providing PROTECTION through its clotting mechanisms and immune defenses.( White Blood cells)


What are 6 characteristics of blood?

1. Blood is more dense and viscous (thicker) than water.
2. Has a temperature of 38 degree C (or 1 degree C higher than oral or rectal body temp)


What are 6 characteristics of blood?

3. Slightly Alkaline (OH- > H+) PH ranging from 7.35 to 7.5
4. Change from dark to bright red depending on oxygen content.


What are 6 characteristics of blood?

5. 55% of blood is plasma and it volume constitutes roughly with 2 things
5.1 Extracellular fluid (ECF) 25%
5.2 Interstitial fluid (ISF) 75%


What are 6 characteristics of blood?

6. Average Blood volume
6.1 Males -- 5to6 liters or about 1.5 gal
6.2 Female - 4to5 liters or about 1.2 gal
6.3 Difference mainly due to Body size.


What is blood means?

Blood is a type of connective tissue.


Blood composed with what 2 things?

1. Plasma 55%
2. Formed elements 45%


what does Interstitial fluid (ISF 75%) works in our blood (plasma volume)?

1. Fluid that bathes body tissues
2. Constantly renewed by blood.


one of components of blood is a plasma, what are 2 characteristics of plasma?

1. it is a watery liquid extracellular matrix that contains dissolved substances.
2. about 91.5% is a water and other 8.5 % is solutes.


what is description and function of water (91.5%)?

-It is a liquid portion of blood.
-Solvent and suspending medium. Absorbs, transports, and releases heat.


The solutes that has 8.5% of plasma, what is the majority of the solutes in a plasma.



What is the specific protein confined blood called?

Plasma Protein.


Most of the plasma proteins are produce by what organ system?



what are functions of plasma proteins?

- Responsible for colloid osmotic pressure. (electrolytes solutes)
- Major contributors to blood viscosity.
- Transport hormones (steroid), fatty acids, and calcium.
- Help regulate Blood pressure ( part function from Carbon dioxide gas)


what is the most important function of the plasma protein.

it is contribution to the maintenance of proper blood osmotic pressure.


8.5 % in a plasma is solutes, beside plasma protein, what else is in solutes?

Electrolytes, Nutrients, Gasses, Regulatory substances, and waste products.


8.5% of plasma is Solutes, how many % is a protein, and what is the rest in the solutes

7% of solutes is proteins,
and the rest 1.5% are electrolytes, Nutrients, gases, regulatory substances, waste products.


what are contain in plasma protein (7% of solute part of 8.5% of all solutes)?

1. Albumins 54%
2. Globulins38%
3. Fibrinogen 7%


What is the description of Albumin (54% in a plasma protein)?

Smallest and most numerous of proteins.


What is the description of Globulins (38% in a plasma protein)?

Large proteins ( plasma cells produce immunoglobulins)


What is the function of Globulins (38% in a plasma protein)

Immunoglobulins help attack viruses and bacteria. Alpha and beta globulins transport iron, lipids, and fat-soluble vitamins.


What is the description and function of Fibrinogen ( 7% of plasma protein)?

- Large protein
- Play essential role in blood clotting.


What is the description of the Electrolytes (part of 1.5% in other solutes)?

It is an organic salts: Positively charged (cations)Na+, K+, Ca2+, Mg2+
And negatively charged (anions) Cl-, HPO4 2-, So4 2-, HCo3 -


What is the description of the Electrolytes (part of 1.5 % in other solutes)

Help maintain osmotic pressure and essential roles in cell function.


What is the description of Nutrients ( part of 1.5% in other solutes)?

Products of digestion, such as amino acids, glucose, fatty acids, glycerol, vitamins and minerals.


What is the function of Nutrients (part of 1.5% in other solutes)?

Essential roles in cell functions, growth, and development.


What is the description of Gases( part of 1.5% in the other solutes)?

Oxygen O2
Carbon dioxide Co2
Nitrogen N2


What is the function of Gases ( part of 1.5% in other solutes)?

- Oxygen is important in many cellular functions.
- Carbone dioxide is involved in the regulation of blood PH.


What is the description and function of Regulatory substances? (part of 1.5 % in the solutes)

Enzymes--Catalyze chemical reactions
Hormones-Regulate metabolism, growth,development
Vitamins-cofactors for enzymatic reactions.


What is the description of waste products?

Urea, uric acid, creatine, creatinine, bilirubin, ammonia.


What is the function of waste products?

Most are break down products of protein metabolism that are carried by the blood to organs of excretion.