Chapter 5: integument

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1

epidermis + dermis =

skin

2

1. skins primary function
2. other functions are (3)

1. protection
2. a. prevention of water loss
b. temp regulation
c. sensory receptor

3

lamina propera

dermis of a mucous membrane

4

keratinocyte

produce keratin : water proofing proteint

5

Merkle cell
A. are?
B. located?

A. tactile cell: sensitive to touch when compressed
B. most abundant in stratum basal but found all over the stratum

6

Langerhans Cells
A. are?
B. located?

A. dendritic cells (antigen-presenting immune cells)
B. in all layers of the epidermis, but are most prominent in the stratum spinosum

7

Melanocytes
A. are?
B. located?

A. pigment producing cells
B. stratum basal

8
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9
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10

Stratum Basal =
1. What cells are present in this layer? (3)

= the deepest layer
1.A. keratinocytes B. Melanocytes C. Merkle cell

11

Stratum Spinosum =
1. what cells are present in this layer?

= second deepest layer
1.A. keratinocytes B. Merkle cell

12

Stratum Granulosum =
1. what occurs in this layer?

= 3rd deepest layer (Middle layer) 3-5 cell layers thick.
1. Keratinization

13

Keratinization

1. keratin filaments begin to develop + cells become thinner and flatter
2. Membranes thicken + become less permeable
3. nucleus and organelles disintegrate
4. finished biproduce = tightly interlocked layer of keratin fibers sandwiched btw thickened phospolipid bilayer

14

Stratum Lucidum =
1. where is this layer found?

=(clear layer)2-3 cell layers thick
1. palms of hands and soles of feet

15

Stratum Corneum =
1. What kind of cells?

= Most superficial layer, 20-30 cell layers thick.
1. corneocytes: dead, scaley interlocked keratinized cells

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17

Basal Cell Carcinoma:
1. Most...
2. Is __ dangerous
3. Originates in...
4. usually occurs on what part of the body?
5. Treatment?

1. common type of skin cancer
2. least
3. stratum basal
4. face
5. surgical removal

18

Squamous Cell Carcinoma:
1. originates in...
2. affects what cells?
3. usually occurs on what part of the body? (4)
4. treatment?
5. could...

1. stratum spinosum
2. keratinocytes
3. scalp, ears, lower lip, or back of hand
4. surgical removal and early detection
5. metastasize

19

Melignant Melanoma
1. is __ dangerous
2. what cells does it affect?
3. usually occurs where?
4. treatment?

1. most
2. melanocytes
3. preexisting mole
4. early detection and surgical removal, chemotherapy, radiation therapy, interferon therapy

20

Melignant Melanoma
signs (4)

1. Asymmetry - one half of a mole or birthmark does not match the other
2. Border - edges are notched, irregular, blurred, or ragged
3. Color - color is not uniform (different shades)
4. Diameter - affected area is larger than 6mm or is growing larger

21

First degree burn
1. affects
2. symptoms

1. only the epidermis
2. redness, pain, and slight edema (swelling)

22

second degree burn
1. affects
2. symptoms

1. the epidermis and parts of the dermis
2. appears red, tan, or white, blistered and painful

23

third degree burn
1. affects
2. symptoms

1. epidermis, dermis, and subcutaneous layer
2. these layers are destroyed