Chapter 5: integument
epidermis + dermis =
1. skins primary function
2. other functions are (3)
2. a. prevention of water loss
b. temp regulation
c. sensory receptor
dermis of a mucous membrane
produce keratin : water proofing proteint
A. tactile cell: sensitive to touch when compressed
B. most abundant in stratum basal but found all over the stratum
A. dendritic cells (antigen-presenting immune cells)
B. in all layers of the epidermis, but are most prominent in the stratum spinosum
A. pigment producing cells
B. stratum basal
Stratum Basal =
1. What cells are present in this layer? (3)
= the deepest layer
1.A. keratinocytes B. Melanocytes C. Merkle cell
Stratum Spinosum =
1. what cells are present in this layer?
= second deepest layer
1.A. keratinocytes B. Merkle cell
Stratum Granulosum =
1. what occurs in this layer?
= 3rd deepest layer (Middle layer) 3-5 cell layers thick.
1. keratin filaments begin to develop + cells become thinner and flatter
2. Membranes thicken + become less permeable
3. nucleus and organelles disintegrate
4. finished biproduce = tightly interlocked layer of keratin fibers sandwiched btw thickened phospolipid bilayer
Stratum Lucidum =
1. where is this layer found?
=(clear layer)2-3 cell layers thick
1. palms of hands and soles of feet
Stratum Corneum =
1. What kind of cells?
= Most superficial layer, 20-30 cell layers thick.
1. corneocytes: dead, scaley interlocked keratinized cells
Basal Cell Carcinoma:
2. Is __ dangerous
3. Originates in...
4. usually occurs on what part of the body?
1. common type of skin cancer
3. stratum basal
5. surgical removal
Squamous Cell Carcinoma:
1. originates in...
2. affects what cells?
3. usually occurs on what part of the body? (4)
1. stratum spinosum
3. scalp, ears, lower lip, or back of hand
4. surgical removal and early detection
1. is __ dangerous
2. what cells does it affect?
3. usually occurs where?
3. preexisting mole
4. early detection and surgical removal, chemotherapy, radiation therapy, interferon therapy
1. Asymmetry - one half of a mole or birthmark does not match the other
2. Border - edges are notched, irregular, blurred, or ragged
3. Color - color is not uniform (different shades)
4. Diameter - affected area is larger than 6mm or is growing larger
First degree burn
1. only the epidermis
2. redness, pain, and slight edema (swelling)
second degree burn
1. the epidermis and parts of the dermis
2. appears red, tan, or white, blistered and painful
third degree burn
1. epidermis, dermis, and subcutaneous layer
2. these layers are destroyed