Autonomic Nervous system drugs

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Pharmacology
Chapters 6-8
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1

1.Cholinergic (parasympathetic ) drugs
produce same effects as Acetylcholine

Sub classification:

acetylcholine, bethanecol, neostigmine, guanidine.

example:.Bacolfen, Diaxepam, Dantrolene

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2.Cholinergic blocking drugs

Sub Classification:
Atropine, scopolamine
Examples
2. Pancuronium, Tubocurarine, Succinylcholine

3

3.Adrenergic drugs

activated by, characteristic of, or secreting epinephrine or related substances, particularly the sympathetic nerve fibers that liberate norepinephrine at a synapse when a nerve impulse passes.

4

Adrenergic drugs( sub class, and examples)

Sub Classification:
catecholamines, noncatecholamines

Example:
Benztorpine, Diphenhydramine, Levodopa, Carbidopa-levodopa

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4. Catecholamines

Catecholamines have excitatory effects on smooth muscle cells of the vessels that supply blood to the skin and mucous membranes and have inhibitory effects on smooth muscle cells located in the wall of the gut, the bronchial tree of the lungs, and the vessels that supply blood to skeletal muscle

6

5.Noncatecholamines(sub class, and examples)

Sub Classification:
(Albuterol, terbutaline)
Examples:
Sumatriptan, Rizatriptan, Ergotamine

7

Catecholamines (sub class, and examples)

Sub Classification:
Dobutamine, dopamine

Examples :4. Phenytoin, Phenobarbital, Carbamazepine, Clonazepam, Valproic acid

8

Noncatecholamines

adrenergic drugs which do not contain the catechol nucleus but still activate, directly or indirectly, the α- and β-receptors

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6. Adrenergic blocking drugs

a.Alpha-adrenergic blockers
Ergotamine, phentolamine
b. Beta-adrenergic blockers
Propanolol, labetalol