Microbiology Lecture Chapter 24- Microbial Diseases of the Respiratory System

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1

Does the URS and LRS have normal microflora?

The URS system does

2

The most common portal of entry is the

the respiratory system

3

_________ are localized phagocytic cells in the LRS.

Alveolar macrophages

4

True or false. There are 10,000-100,,000 per cough or sneeze.

true

5

Causes of aerosolization of microbes sneezing, coughing, talking etc. Why

water droplets are expelled
evaporate to about 1 -4 um.
contain
-microbes and mucous

6

Aerosolized microbes are typically from:

Outdoor:
soil water plants people
Indoor:
people pets

7

Microbes in the air:

air is not a growth medium
gram (+) is resistant to drying (Strep-Staph, Mycobacterium- waxy cell wall hard to penetrate)
effective transmittal occurs over short distance

8

Protective mechanisms of the Respiratory system

lungs are housed in a 2 layer sac called the pleura
Normal microflora in URT
Ciliary escalator
alveolar macrophages

9

Common infections of the URT which are usually caused by staph and strep

pharyngitis
laryngitis
tonsillitis
sinusitis
Epiglottitis

10

Bacterial diseases of URT

Streptococcal pharyngitis (strep throat)
scarlet fever
diphtheria
otitis media

11

____ and ______ are important respiratory pathogens.

Streptococcus pyogenes
Streptococcus pneumoniae

12

Streptococcus can be found in healthy carriers and negative activities prevented by _________.

microflora

13

Virulent strains of streptococcus are:

encapsulated
produce hemolysins
sever sore throat, malaise, enlarged tonsils, etc.
Bacteriophage gene----> exotoxin

14

Diphtheria is caused by

corynebacterium diphtheria and is pleomorphic- changes in different environments

15

In diphtheria the exotoxin destroys _______.

tissue

16

TB study slides on PPT

study PPT