What are the three hormones that are produced by the thyroid gland?
- T3
- T4
- Calcitonin
What is the action of calcitonin?
- Decreases serum calcium by taking calcium out of the blood and pushing it back into the bone
What thyroid disease has “too much energy”?
- Grave’s disease (hyperthyroidism)
What are the signs and symptoms of Graves’ disease?
-
Mind
- Nervous/irritable
- Low attention span
-
Weight
- High appetite
- Weight loss
- Fast GI tract -> diarrhea and increased bowl sounds
-
Vitals
- Tachycardia
- High BP
- Exophthalmos
- Arrhythmia/palpitations
- Thyroid size bigger
What type of eye care is needed for someone with Graves’ eye disease?
- Wear sunglasses
- Apply cool compresses for moisture
- Lubricating eye drops
- Elevate HOB auto reduce swelling
- Steriods and/or surgery
For the diagnosis of Graves’ disease, what would T4 (thyroxine) and TSH look like?
- T4 increased
- TSH decreased
What disease has T4 levels increased and TSH decreased?
- Graves’
What instructions should a pt follow if they are getting a thyroid scan?
- They must discontinue any iodine containing medication 1 week prior to the thyroid scan and must wait 6 weeks to restart iodine medications
What are the treatments for Graves’ disease?
- Anti-thyroids
- methimazole
- propylthiouracil
- Iodine Compounds
- potassium iodine
- Beta Blockers
- propanolol
- Radioactive Iodine therapy
- Thyroidectomy (partial/complete)
What is the action for methimazole and propylthiouracil?
- Single dose with less side effects
- Stops the thyroid from making thyroid hormones
- Used pre-op to stun the thyroid
What drug decreases the size and the vascularity of the thyroid gland?
- Potassium iodine
What patient teaching should given when taking potassium iodine?
- Give in milk or juice and must use a straw or it will stain teeth
What class of drugs decreases myocardial contractility and decreases BP and HR?
- Beta Blockers
What class of drugs should you not give to asthmatics or diabetics because they mask hypoglycemia symptoms?
- Beta blocker
What is the action of radioactive iodine therapy?
- Curative procedure that destroys thyroid cells and stops making thyroid hormones
Must rule out what for a pt to have radioactive iodine therapy?
- Rule out pregnancy first
What are the precautions for radioactive iodine therapy?
- Stay away from babies for 1 week
- Don’t kiss anyone for 1 week
What is the post op priority for thyroidectomy?
- Signs of hemorrhage
What does it mean when the pt reports feeling pressure on their neck after thyroidectomy?
- Pt is hemorrhaging
Where should the nurse check for hemorrhaging after a thyroidectomy?
- Look for pooling at the back of the neck and at incision site
How could a nurse assess for recurrent laryngeal nerve damage after a thyroidectomy?
- By listening for hoarseness and a weak voice
- look for a change in voice
What could recurrent laryngeal nerve damage lead to?
- Vocal cord paralysis
- When there is paralysis of both cords, air obstruction will occur requiring immediate trach
What must be at bedside after a thyroidectomy?
- Trach set
What electrolyte imbalance can occur after a thyroidectomy?
- Hypocalcemia
- Parathyroid could have been removed
- Signs: rigid tight muscles, tetany, seizures, laryngeal spasms
What are the signs and symptoms of hypothyroid?
- No energy
- Myxedema (waxy and swelling skin)
- Fatigue
- No expression
- Speech slurred
- Weight gain
- Slow GI
- Cold
- Amenorrhea (no period)
- Vital signs
- Low BP
- Bradycardia
What disease has decreased levels of T4 and increased levels of TSH?
- Hypothyroidism
What is drug that treats hypothyroidism?
- Levothyroxine
Is levothyroxine pregnancy safe?
- Yes
What medications can impair the absorption of levothyroxine?
- Antacids
- Calcium
- Iron preparations
How long do you need to take levothyroxine?
- For the rest of your life
What are the four actions of glucocorticoids?
- Changes the mood
- Suppresses the immune system and inflammatory response
- Regulates glucose metabolism
- Breakdown fats and proteins
- Inhibits insulin
- Hyperglycemic
- Do blood glucose montioring
- May need insulin when on steroids
What does aldosterone make you retain and makes you lose?
- Retain: Salt and water
- Lose: Potassium
What are the signs and symptoms for Addison’s disease?
- Mind and body
- Weight
- Blood pressure
- Electrolyte imbalances
- Glucose (hypo or hyper)
- Skin conditions
- Extreme fatigue
- Confusion
- Nausea, vomiting, and diarrhea
- Anorexia/weight loss
- Hypotension
- Hyponatremia
- Hyperkalemia
- Hypoglycemia
- Hyperpigmentation (bronzing color of the skin and mucous membranes)
- Vitillgo
Do you increase or decrease sodium intake for pt with Addison’s disease?
- Increase
How are doses given for corticosteroids?
- Given twice a day in split doses
- Client will take 2/3 of the dose in the morning and 1/3 of the dose in the evening
What are the signs and symptoms of Cushing’s?
- Mind
- Body changes
- Glucose (hyper or hypo)
- Electrolyte imbalance
-
Mind
- Psychosis to depression
-
Body changes
- Lipolysis (Thin extremities/skin)
- Moon faced (fat redistribution or fluid retention)
- Truncal obesity (fat redistribution; lipogenesis)
- Buffalo hump
- Abdominal striae
- Weight gain
- Oily skin/acne
- Women with male traits (hirsutism)
- Growth arrest
-
Glucose (hypo or hyper)
- Hyperglycemia
-
Electrolyte imbalance
- Hypokalemia
Would cortisol levels be high or low in a pt with Cushing's?
- High
Is Cushing's a fluid volume excess or deficit problem?
- Fluid volume excess
What is the treatment for Cushing's?
- Adrenalectomy (unilateral or bilateral)
- Quiet environment (can't handle stress)
What is the diet for a pt. with Cushing's?
- High potassium foods
- Low sodium foods
- High protein
- High calcium
What is the blood glucose levels with diabetes?
- <140 mg/dL
- 80-130 mg/dL
What can be the first sign of Type 1 diabetes?
- DKA
What are the three p's of Type 1 diabetes?
- Polyuria
- Polydipsia
- Polyphagia
What acid-base problem occurs with someone with uncontrolled type 1 diabetes?
- Metabolic acidosis
Polyuria can lead to _______
- Shock
Do oral hypoglycemic agents work for Type 1 diabetics?
- No
When are pregnant women screened for gestational diabetes?
- 1st prenatal visit
- At 24 to 28 weeks gestation
What are complications for the baby with a mother who has gestational diabetes?
- Increased birth weight
- Hypoglycemia
What is the normal A1C?
- About 5
What would be the A1C levels if the pt had type 1 diabetes?
- HbA1C 6.5 +
What is the fasting plasma glucose?
- Normal
- Diabetic
- Normal
- 99 or below
- Diabetic
- 126 or above
What are the signs and symptoms of DKA?
- Hyperglycemia
- Dehydration
- Kussmaul respirations
- Acid breath "fruity breath"
What is the criteria for metabolic syndrome?
- Waist circumference
- Lipids
- Blood pressure
- Fasting blood sugar
-
Waist circumference
- Female: > 35 in
- Male: > 40 in
-
Lipids
-
Triglycerides
- > 150 mg/dL
-
HDL
- Males:< 40 mg/dL
- Females < 50 mg/dL
-
Triglycerides
-
Blood pressure
- 130/85
-
Fasting blood sugar
- > 100 mg/dL
What syndrome is known to increase the risk for developing type 2 diabetes and cardiovascular disease?
- Metabolic syndrome
What can help with glycemic control in a diabetic diet?
- Client should be taught how to count carbohydrates
What should be included in a diabetic diet?
- Counting carbs
- Carbs should include fruits, vegetables, whole grains, and low fat dairy
- High fiber
foods
- Eliminates the sharp rise/fall in BS
Describe the Plate Method
- 9 inch plates
- Fill 1/2 with non-starchy vegetables
- 1/4 with carbs
- 1/4 with protein
What should the client do pre-exercise to prevent hypoglycemia?
- Eat something before
What is the action of Metformin?
- Reduces glucose production and enhances how glucose enters the cell
What should a pt do if undergoing surgery or any radiologic procedure that involves contrast dye and taking metformin?
- Termporaily discontinue metformin
- Resume 48 hrs after procedure if kidney function has returned and the creatinine level is normal
What are signs of hyperglycemia?
- Polyuria
- Polydypsia
- Polyphagia
- Hot and dry skun
- Slow wound healing
- vision changes
What are acute causes that can cause hyperglycemia?
- Sepsis (infection)
- Stress (surgery, hospital stay)
- Skip insulin
- Steroids
What are signs of hypoglycemia?
- Cool
- Diaphoretic "clammy"
- Pale
- Nervous "anxious" "trembling"
- Irritable
- Weakness
- Hunger
- Headache
If hypoglycemic and awake, what should the pt take?
- Eat simple carbohydrates (15 grams)
- Juice, soda, crackers, low fat milk
- Not fat milk or peanut butter
- glucose absorption is delayed with foods with lots of fats
- 15 gram of simple carb -> wait 15 min, if < 70 mg/dL -> 15 grams of sugar
If hypoglycemic and unconscious, what should the nurse do?
- Push D50W IV
- Injectable glucagon (subq, IM, IV)
- Reassess in 15 min
What are causes for hypoglycemia?
- Exercise (diabetics)
- Alcohol
- Insulin PEAK times
What are the complications of diabetes?
-
Renal failure
- Indicated by creatinine over 1.3
- Over 1.3 means kidney failure
-
Peripheral neuropathy
- Nerve damage in the extremities
- Diabetic feet -> gangree
-
Retinopathy
- Can lead to blindness
-
Heart
- Hypertension and atherosclerosis
When should you give a patient a food if they are taking insulin?
- Give foods during peaks
What is the onset, peak, and duration for long acting insulin?
- Onset: 1-2 hrs
- Peak: None
- Duration: 24 hrs
What is the onset, peak, and duration for NPH?
- Onset: 1-2 hrs
- Peak: 4-12 hrs
- Duration: 18 - 24 hrs
What is the onset, peak, and duration for regular insulin?
- Onset: 30-60 min
- Peak: 2-4 hrs
- Duration: 5-7 hrs
What is the onset, peak, and duration for rapid insulin?
- Onset: 5-30 min
- Peak: 30-90 min
- Duration: 3-5 hrs
What insulin cannot mix with other insulins?
- Long acting
- Determir and Glargine
What insulin has the highest risk for hypoglycemia?
- Rapid
- Lispro, aspart, glulisine
What insulin has the lowest risk for hypoglycemia?
- Long acting - glargine and detemir
What insulin is given only IV?
- Regular
Detemir =
- "Lasts All Year"
How to mix regular and NPH insulin?
- clear to cloudy
What insulin cannot be given in an IV?
- NPH
What should a diabetic avoid in their diet?
- Simple sugars
- Soda, candy, white bread, juices, pastas, fries, low fat milk
What should a diabetic have in their diet?
- Good carbs
- High fiber (complex carbs)
- BROWN - beans, rice, bead, peanut butter
- WHOLE - whole wheat/grain/milk
What type of diabetes leads to DKA?
- Type 1 diabetes
What type of diabetes leads to Hyperglycemic hyperosmolar non-ketotic syndrome (HHNS)?
- Type 2
Does Hyperglycemic hyperosmolar non-ketotic syndrome (HHNS) produce ketones?
- No
What are causes of DKA?
- Sepsis (infection)
- Sickness
- Stress (surgery)
- Skip insulin
What are the are the signs and symptoms of DKA?
- Dry and high sugar 250-500+
- Ketones and Kussmaul respirations -> rapid fruity breath
- Abdominal pain
- Metabolic acidosis (pH 7.35 or less)
What are the signs and symptoms of HHNS?
- High sugar (over 600+)
- Extreme dehydration
- Neurological manifestations - confusion
What is the priority action for DKA and HHS?
- Treat the dehydration first
- 0.9% normal saline
What is the treatment for DKA?
- Treat the dehydration first
- 0.9% normal saline
- Lower the sugar slowly
- Hourly BS checks
- Over 250 BS = IV regular insulin only
- Below 200 BS = IQ insulin + D50 IV
- Add potassium (even if
normal)
- DURING IV insulin
What is the treatment for HHNS?
- Treat the dehydration first
- 0.9% normal saline
- Insulin IV = Only regular insulin