Infective Endocarditis Flashcards


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created 1 year ago by abedfordpowell
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1

What are two main risk factors for IE?

1. Presence of prosthetic valve

2. Previous endocarditis

2

What is the most common organism in IE?

Coagulase + Staph

3

Hallmark finding of IE?

HIGH GRADE BACTEREMIA - 3 SETS OF BLOOD CULTURES SHOULD BE COLLECTED OVER 24 HOURS

STIGMATA ON PE

4

Which echocardiogram has higher sensitivity?

TEE

- more invasive and costly

5

Right sided IE:

Tricuspid and pulmonary valve

6

Which IE is associated with IV drug users?

Right sides

7

Left sided IE:

Mitral and aortic valves

8

The Duke criteria should be used to replace clinical judgement?

False

9

Major criteria (Duke):

1. Blood culture + for IE (s. aureus, viridans, strept Boris, HACEK)

2. Echocardiogram + for IE

10

Minor criteria:

Predisposing heart condition

IV drug use

Fever

Vascular phenomena

Immunologic phenomena

Blood culture + but does not meet major criteria

11

Definite IE:

2 major criteria

1 major criteria and 3 minor criteria

5 minor criteria

12

Possible IE

1 major and 1 minor

3 minor

13

Rifampin is a therapeutic option in strept IE?

FALSE!!

Staph only!!!

14

Monotherapy is effective for enterococcal endocarditis?

False!

15

Advantages of synergy therapy?

1. Allows the body to more rapidly clear difficult infections

2. Can use lower doses of AB for lower duration of therapy

3. Combined resistance

4. Increased enterococcal cell permeability