UTI Flashcards


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created 1 year ago by abedfordpowell
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1

Lower UTI would be describing:

cystitis

2

UPPER UTI would be describing:

Pyelonephritis

3

Uncomplicated UTI patient:

Premenopausal woman who is not pregnant with no known urological abnormalities

4

Morbidity associated with UTI's

Recurrent infections

Progression to urosepsis/bacteremia

Permanent renal damage

ADEs and resistance

5

Risk factors for UTI's:

History of UTI

Sex within the last 48 hours

Uncontrolled DM

Female <35 or >65

SGLT2i

Abnormalities

Manipulation

6

What is the most common infection type?

Ascending

7

Etiologies associated with UTIs:

Staph. saprophytic

Klebsiella

E. coli

Proteus- 50 years old

Enterobacteriaceae

Candida and enterococcus- DM, catheter

8

Clinical presentation of cystitis:

Dysuria

U. frequency

u. urgency

Supapubic tenderness

Gross hematuria

9

Clinical presentation of pyelonephritis:

SIGNS AND SYMPTOMS OF CYSTITIS

PLUS

Flank pain

Fever

Costovertebral tenderness

N/V

Malaise

10

UTI's may also present in unique populations as:

Altered mental status

Decreased appetite

GI symptoms

11

5 criteria for a "good" diagnostic test for UTIs:

1. Bacteruria: >100,000 CFU

2. Leukocyte esterase (+)

3. Nitrates (+)

4. (-) squamous epithelial cells

5. WBC >1

12

Non-pharm options for UTIs:

1. Voiding after intercourse

2. Hydration

3. Cranberry juice

4. Lactobacillus

5. AZO 200 mg TID x 1-2 days for symptom relief

13

Which two agents are used for cystitis only?

Macrobid and fosfomycin

14

Macrobid:

Bacterial reduction causing metabolites

100 mg BID x 5 days

15

ADE's of Macrobid?

GI intolerance

Pulmonary toxicity

16

What is the CrCl cutoff for Macrobid?

<30 mL/min

17

When should Macrobid be avoided?

1st trimester

and

At term (38-42 weeks) due to G6PD

18

When would fosfomycin (Monurol) be a good option for cystitis?

DRUG RESISTANT organisms

and

Pregnancy

19

Fosfomycin:

Inactivated perusal transferase enzymes

3g x1 dose

20

Which two agents can treat cystitis and pyelonephritis?

Bactrim and beta-lactams

21

When should be Bactrim use be avoided?

>20% resistance

22

Which agent should be avoided in the 3rd trimester due to G6PD?

Bactrim

23

Bactrim:

160mg/800 mg PO BID

24

Which 2 fluroquinolones are used in cystitis?

Cipro and levo

25

Which agents should be avoided in uncomplicated UTI's?

fluroquinolones

26

Which agents are a practical 1st line for UTI's due to spectrum, efficacy?

Beta lactams

27

Amoxicillin or ampicillin can be used alone for UTI's?

False

28

What is a common BL used in the inpatient setting as a one time dose for pyelonephritis?

Cetriaxone

29

What is the preferred agent in pregnancy for UTIs?

Beta lactams

30

Complicated UTIs should be treated using what form of administration?

IV

31

Treatment of complicated UTI's?

1. Extended spectrum cephalosporins (Ceftriaxone, Cefepime)

2. IV fluroquinolones

3. IV ahminoglycosides, BL/BLI, carbapenems, aztreoman

32

Men with complicated UTI's should be treated for how long?

10-14 days (up to 4-6 weeks)

33

Which two agents should be used in complicated UTI's in men?

Bactrim + quinolone

34

Which patients should be screened and treated for asymptomatic bacteriuria?

1. Pregnant women

2. Patients undergoing endourological procedures (TURP)

35

Etiology of prostatitis:

K.E.P

36

Acute prostatitis:

Fever, chills, malaise, myalgia, dysuria, polyuria, nocturne

37

Chronic prostatitis:

Asymptomatic, difficulties voiding, low back pain

38

Treatment of prostatitis:

Are you down with FBB?

Fluoroquinolones (cipro/levo)

Bactrim

B-lactams