1/12 immunology Flashcards


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created 1 year ago by bitchalaureate_of_science
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updated 1 year ago by bitchalaureate_of_science
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immunology
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1

humoral immunity

immunity in the body fluid, mediated by macromolecules like antibodies, complement proteins, antimicrobial peptides

2

opsonization

coating a surface of bacteria to make it more recognizable to the immune system

3

type of immunity that B lymphocytes are

humoral (secrete Ig eventually)

4

type of immunity that T lymphocytes are

cell-mediated (never secrete TCRs)

5

B cell effector cells

plasma cells (antibody factories)

6

T cell effector cells

cytotoxic T cells, helper T cells (make cytokines), regulatory T cells

7

complement system

serum proteins, ingest pathogens (phagosome), lyse pathogens (lysosome)

8

where b cells develope

the bone marrow

9

where t cells develope

the thymus

10

what lymphoid system B and T cells are part of

Central lymphoid system

11

what type of immunity the peripheral lymphoid system is associated with

adaptive lymphoid system

12

what organs are in the peripheral lymphoid system

lymph nodes, spleen, MALT

13

how lymphocytes move without infection verses with infection

without infection they move around the body and survey for pathogens, with infection they stay and develop a response

14

where dendritic cells bring pathogens

the draining lymph nodes

15

lymph node reaction to pathogen

clonal expansion (they get bigger)

16

three phases of immune response

innate phase, induced innate response, adaptive immune response

17

where every immune response happens before the adaptive immune response kicks in

at the site of the infection

18

adaptive immune response

slow response, variable pathogen recognition, highly selective and specific, improve during response

19

innate immune response

rapid response, fixed pathogen recognition, limited specificity, constant during response

20

extracellular pathogens

bacteria, viruses, fungi, parasites

21

intracellular pathogens

all viruses, some bacteria

22

effector response to intracellular pathogens

kill infected host cell

23

how pathogens damage tissue

direct damage from secreted toxins, lysis from being forced to produce foreign material, destroyed by immune response

24

defensins on the skin

beta defensins (S)

25

defensins in the gut

alpha defensins (G)

26

defensins in the lungs

alpha defensins (L)

27

defensins in the eyes/nose/oral cavity

beta defensins (E)

28

defensins makeup

cationic peptides

29

what alpha defensins are made by

Paneth cells, stored in neutrophils

30

what beta defensins are made by

epithelia of skin, respiratory tract, urogenital tract

31

what makes plasma proteins

the liver makes them constitutively

32

three functions of the complement system

pattern recognition, protease cascade, direct pathogen lysis