opioid and non opioid analgesics

Helpfulness: 0
Set Details Share
created 13 days ago by AmberParks541
9 views
updated 13 days ago by AmberParks541
show moreless
Page to share:
Embed this setcancel
COPY
code changes based on your size selection
Size:
X
Show:
1

five cardinal signs of inflammation

redness

swelling/edema

heat

pain

loss of function

2

analgesis

prescribed for pain relief

3

nociceptors

pain that originates from tissues

4

neuropathic

pain that originates from nerves

5

chronic pain

greater than 3 months (some sources say 6)

6

things that influence pain tolerance

age

gender

culture

ethnicity

previous experience

anxiety level

specific circumstances such as a traumatic event

7

somatic pain

originates from musculoskeletal joint cutaneous nociceptors and is often localized

8

visceral pain

originates in nociceptors located in hallow organs and smooth muscle

9

Abbreviation for non-steroidal anti-inflammatory

NSAID

10

examples of NSAIDs on out list

asprin

naproxen

ibuprofen

11

antipyretic means

lowers fever

12

Other names known for Asprin

Acetylsalicylic acid and ASA

13

symptoms of asprin overdose

ringing in the ears, nausea, vomiting, drowsiness, confusion and rapid breathing

14

what does the treatment for asprin involved

activated charcoal by mouth or stomach tube, iv fluids and bicarbonate

Hemodialysis for severe poisoning

15

action of asprin

inhibits biosynthesis of prostaglandins

inhibits cox-2 decreases inflammation and pain

inhibits cox-1 decreases protection of the stomach lining

16

unique fact about asprin

its a drug of choice for pain and arthritic inflammation and decreases platelet aggregation

17

drug-drug interactions for salicylates

increased bleeding with anticoagulants and other NSAIDS

risk for hypoglycemia with oral antidiabetics

increased risk for gastric ulcer with glucocorticoids

decreased effects of ACE inhibitors, loop diuretics and probencid

effects are decreased by corticosteroids

18

drug lab interactions for salicylates

increased pt, bleeding time, INR uric acid

decreased cholesterol. t3 and t4 levels

19

Foods containing salicylates

prunes, raisins, licorice

certain spices such as curry and paprika

20

why do you not give asprin to children with flu or virus like symptoms?

it may lead to reye syndrome

21

side effects/ adverse reactions to asprin

REYE SYNDROME, HEPATOTOXICITY

HYPERSENSITIVITY: TINNITUS, DIZZINESS, BRONCHOSPASMS

GI distress, bleeding, stomach ulcers, drowsiness and headache

HEMOLYTIC ANEMIA, thrombocytopenia, leukopenia agranulocytosis

22

How long before surgery should you stop taking asprin?

7 days

23

Indomethacin (indocin) action and use

inhibits prostoglandin synthesis

used in treatment of rheumatoid arthritis, osteoarthritis and gouty arthritis

24

what is indomethacin/ its classification

a para-chlorobenzoic acid

NSAID

antiheumatic

25

asprin classification

antipyretic

non-opioid analgesic

salicylate

26

unlabled use for asprin

adjunctive treatment of Kawasaki disease

27

important thing to watch out for with indomethacin

watch out for cardiovascular thrombic events

28

side effects and adverse reactions associated with indomethacin

dizziness, headache, weakness, GI distress and bleeding.

sodium and water retention

hypertension

29

diclofenac/ ketorolac (Tordol) are ?

phenylacetic acid derivatives

30

diclofenac/ ketorolac (TORODOL) action

Inhibits prostoglandin synthesis

31

uses of diclofenac/ ketorolac (TORDOL)

rheumatoid arthritis. osteoarthritis. ankylosing spondylitis and PAIN

32

ketorolac (TORODOL) should not be used longer than 5 days true or false

True it is recommended for short-term management of pain

33

what is the brand name for ibuprofen

MOTRIN

34

classifications of ibuprofen

NSAID

antipyretic

(may be antirhumatic)

non opioid analgesic

35

action of ibupofen

prostaglandin synthesis inhibition

36

true or false ibuprofen is the most widely used NSAID

true

37

what else is ibuprofen

a propionic acid derivative

38

side effect of ibuprofen

gastric bleeding and distress, drowsiness, dizziness, headache, confusion, insomnia, dreams

NEPHROTOXICITY, DYSRHYTHMIAS TINNITUS

39

drug interactions with ibuprofen

increased bleeding with warfarin

increased effects with phenytoin, sulfonamides, cephalosporins

decreased effect with asprin

40

important stand out nursing intervention with ibuprofen

observe patient for bleeding gums, petechiae, ecchymoses, or black tarry stools

41

celecoxib other name

Celebrex

42

action of celecoxib

selectively inhibits cox-2 without inhibiting cox-1

43

things to remember for NSAIDS in older adults

drug interactions are more common

greater incidence of GI distress and ulceration

reduced dose decreases risk of side effects

increase fluid intake for adequate hydration

44

infliximab is

antibody administered IV that is used for treating several chromic inflammatory diseases

45

infliximab classification

antirhumatic

GI antiinflammatory

monoclonal antibodies

46

adverse reactions and side effects with infliximab

stroke, arrhythmias, myocardial infarction and ischemia, infections, sarcoidosis

Malignancies: lymphoma, HSTCL, Leukemia, skin cancer and cervical cancer

47

Gout occurs from

deffect in purine metabolism leading to uric acid accumulation

48

purine containing foods

organ meats, sardines, salmon, gravy, herring, liver, meat soups, ALCOHOL (ESPECIALLY BEER)

49

colchicine classification

anti gout agent

50

action of colchicine

inhibits migration of leukocytes to inflamed site

alleviates gout symptoms and has anti inflammatory properties

51

how do you avoid GI distress with colchicine

take it with food

52

contradictions with colchicine

Severe renal, cardiac or GI problems

53

side effects and adverse reactions related to colchicine

GI distress, agranulocytosis, aplastic anemia,

54

true or false you cannot take colchicine for prophylaxis of gout

false, yes you can

55

lab considerations with colchicine

report significant low blood lab values

56

DRUG FOOD INTERACTION WITH colchicine

GRAPEFRUIT JUICE

57

drug-drug interaction with colchicine

STRONG CYP3A4 inhibitors

58

true or false those with asthma, allergies or nasal polyps have a higher risk of a hypersensitivity reaction from asprin

true

59

allopurinol classifications

anti gout

antihyperuricemic

xanthine oxidase inhibitor

60

indications for allopurinol

prevention of attack of gouty arthritis and nephropathy

61

allopurinol action

decreases uric acid synthesis and prevents gout attacks

62

adverse reactions and side effects associated with allopurinol

steven-johnson syndrome

rash (discontinue at first sign of a rash)

hypo and hypertension

flushing, HF (IV), diarrhea, erectile dysfunction

63

lab test considerations for allopurinol

serum uric acid levels should decrease 2-3 days after initiation of oral therapy

BG monitoring in those taking oral hypoglycemics

Kidney and liver function tests before and periodically during first few months of treatment

64

drug-drug interactions with allopurinol

amoicillin and amoxicillin increase risk of rash

thiazide diuretics and ACE inhibitors increase risk of hypersensitivity reactions

65

nursing process with allopurinol

instruct patient to increase fluid intake and to have a yearly eye exam

66

Other names for acetominophen

Tylenol and APAP

67

is acetominophen and NSAID

NO! it is not an NSAID

68

action of acetaminophen

prostaglandin synthesis inhibition

69

antedote for acetaminophen overdose

acetylcysteine (Mucomyst)

70

acetaminophen classification

antipyretic

non-opioid analgesic

71

Maximum dose of acetaminophen

4G/Day

72

what is APAP short for

N-ACETYL-PARA-AMINOPHENOL

73

true or false acetaminophen has a high incidence of GI distress

False

74

acetaminophen adverse reactions

Hepatotoxicity, renal failure, thrombocytopenia, hemolytic anemia, agranulocytosis, leukopenia and neutropenia

75

side effects of acetaminophen

rash, headache, insomnia,

76

drug-drug interactions with acetaminophen

warfarin can increase bleeding

alcohol is additive to hepatotoxicity

77

true or false

Asprin is anti-inflammatory while Acetaminophen is not

true

78

true or false

both asprin and acetaminophen are both analgesics

true

79

true or false

only acetaminophen is antipyretic while asprin is not

False

80

true of false

Both asprin and acetaminophen decrease platelet aggregation

false

81

how fast can death occur with acetaminophen OD

1-4 days

82

TRAMADOL

analgesic that is centrally acting

83

what schedule class is Tramadol

schedule IV

84

what is unique about an overdose situation with Tramadol

naloxone only reverses half of the effects because Tramadol is not a full "opioid" but is considered opioid

85

sumatriptan classification

vascular headache suppressant

5-HT1 agaonist

86

oxycodone classification

opioid analgesic

87

what schedule is oxycodone

schedule II

88

do not confuse short acting oxycodone with

long acting oxycontin

89

naproxen classification

non opioid analgesic

NSAID

antipyretic

90

adverse reactions and side effects of codine

confusion, sedation, hypotension, constipation, nausea, vomiting

psychological and physical dependance

hypersensitive reactions

91

big drug-drug interaction with codine

MAO inhibitors increase risk of adverse reactions

92

indications for codine

mild-moderate pain

antitussive in smaller doses

93

codine classification

opioid analgesic

allergy, cold, cough and cold remadies

antitussive

94

what schedule is codine

schedule II, III, IV and V depending on content

95

adverse reactions and side effects with buprenorphine

confusion, dysphoria, hallucinations, sedation, sweating and nausea

hepatotoxicity, respiratory depression,

hypersensitivity reactions

96

action of buprenorphine

binds to opiate receptors in CNS

97

indication for buprenorphine

management of moderate-severe acute pain

98

buprenorphine classification

opioid analgesic

99

what schedule is buprenorphine

schedule II

100

what do you give in case of opioid OD

nalaxone (Narcan)

101

adverse reactions and side effects with nalaxone

ventricular arrhythmias

102

nalaxone classification

antidote for opioid OD

103

morphine classification

opioid analgesic

104

what schedule is morphine

schedule II

105

drug-drug interactions with merpidine

MAO inhibitors or Procarbazine

DONT TAKE WITHIN 14 DAYS OF EACHOTHER

106

merpidine adverse reactions and side effects

seizures and hypersensitivity reactions

107

merpidine classification

opioid analgesic

108

what schedule is merpidine

schedule II

109

hydromorphone classification

opioid analgesic

allergy and cold/cough remadies

110

what schedule is hydromorphone

schedule II

111

adverse reactions and side effects of hydrocodone/acetaminophen and hydrocodone/ibuprofen

confusion, sedation, hypotension

constipation, dyspepsia nausea

respiratory depression

112

hydrocodone/ibuprofen and hydrocodone/acetaminophen classification

allergy, cold and cough remedies

opioid analgesic/non opioid analgesic combo

113

what schedule are the combo drugs hydrocodone/ibuprofen and hydrocodone/acetaminophen?

schedule II

114

adverse reactions and side effect of fetanyl

dizziness, drowsiness, headache

respiratory depression, anaphylaxis

constipation, nausea, vomiting

psychological and physical dependance

115

drug-food interaction with fetanyl

grape fruit

116

drug-natural product interaction with fentanyl

st johns wort

117

drug-drug interaction with fentanyl

should not be given with MAO inhibiters within 14 days because of possible severe and unpredictable reactions

118

classification of fentanyl

opioid analgesic

119

what schedule is fentanyl

schedule II