Bailey & Scott's Diagnostic Microbiology: Clinically Significant Yeasts and Yeast-Like Organisms Flashcards


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1

clinically significant yeasts

Candida, Cryptococcus, Trichosporon, Malassezia, Rhodotorula, Saccharomyces, Geotrichum

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dermatophytes

yeasts that cause superficial skin infections; includes Trichosporan and Malassezia

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Geotrichum

opportunistic yeast

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Candida albicans

true pathogen; involved in variety of conditions including oroesophageal, intertriginous (skin infection), paronchia (nails), onychomycosis (nails and nail beds), vulvovaginitis, thrush, pulmonary infection, eye infection, endocarditis, meningitis, and disseminated infection

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Candida albicans

most common cause of yeast infections; can cause disease in any site when host defense is altered

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Candida albicans

creamy white stars "feet"

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Candida albicans

clusters of blastoconidia, pseudohyphae, and terminal chlamydoconidia

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germ tube positive, sucrose positive, urease negative

biochemical results of Candida albicans

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Candida

blastoconidia or pseudohyphae strongly gram positive

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CHROMagar

Candida culture medium

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Candida

causative agent of thrush; indicator of immunosuppression-HIV, prolonged antimicrobial therapy, and chemotherapy; can be serious and become disseminated

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Candida tropicalis

second most common Candida species; aggressive infection and very difficult to treat with traditional antifungals; associated with vaginitis, intestinal disease, systemic infections, UTI, pulmonary infections, thrush, keratitis, and endocarditis;

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Candida tropicalis

creamy, glabrous with mycelial fringe or wrinkled

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Candida tropicalis

single or small random blastoconidia clusters along pseudohyphae; teardrop chlamydoconidia

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Candida parapsilosis

major cause of nosocomial infections-indwelling catheters, vaginitis, endothalmitis, endocarditis, systemic infections, UTI, thrush, keratitis, otomycosis

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Candida parapsilosis

creamy, glabrous, lacy appearance

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Candida parapsilosis

short, crooked or curved pseudohyphae with blastoconidia singly produced or small clusters and giant mycelial or hyphal cells

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Candida krusei

rarely isolated as a cause of endocarditis and vaginitis, UTI, and keratitis

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Candida krusei

pseudohyphae with cross-match sticks and elongated tree-like blastoconidia

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Candida kefyr

one of 4 most frequently isolated associated with endocarditis, vaginitis, and UTI

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Candida kefyr

creamy, smooth

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Candida kefyr

elongated blastoconidia resembling logs in a stream or log jam along pseudohyphae

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Candida guilliermondii

associated with UTI, osteomyelitis, cutaneous, disseminated and endocarditis

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Candida guilliermondii

short pseudohyphae with clusters of blastoconidia at constrictions (septa)

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Candida glabrata

most commonly found as fungemia associated with endocarditis, meningitis, UTIm pulmonary, vaginintis, or other disseminated infection

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Candida glabrata

creamy, smooth, moist

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Candida glabrata

blastoconidia only (on CMT), no pseudohyphae