What is Selective Toxicity? Why is it a good thing when
selecting an antibiotic medication?
A substance that interferes with essential structures common
in microbes but not in human cells. Causes greater harm to microbes
than to humans.
What is Bacteriocidal?
Chemicals that kill bacteria but sometimes only inhibitory
What is Bacteriostatic?
Chemicals that inhibit bacterial growth (sulfa drug)
What is Broad-spectrum?
These antibacterial medications affect a wide range of
bacteria. Important when treating acute life-threatening diseases.
What is Narrow-spectrum?
These antibacterial medications only affect a limited range of
bacteria. Requires identification of bacteria and susceptibility of pathogen.
what is Antagonistic?
Medications that interfere with other medications
What is Synergistic??
Medications that enhance other medications
Adverse effects of antimicrobial medications
Allergic reactions, toxic effects, and dysbiosis (imbalance in the microbiome)
Describe how bacteria can acquire antibacterial resistance mechanisms
Through spontaneous mutation or horizontal gene transfer
What are examples of Beta-Lactam Antiobiotics
How do Beta-lactam antibiotics work?
What are PBPs?
Specific characteristics of Penecillins
Specific characteristics of Cephalosporins
Specific characteristics of Carbapenams
Specific characteristics of Monobactems
Examples of Glycopeptide antibiotics
How do Glycopeptides work?
Examples of Bacitracins antibiotics
How do Bacitracins work?
How does daptomycin work?
How does polymixins work?
What drugs are used for mycobacterium infections?
What are the different mechanisms of acquired resistance?
What are some examples of ways to prevent resistance?
Explain the distribution of antimicrobial medications in the body
Explain the metabolism of antimicrobial medications in the body
Explain the excretion of antimicrobial medications in the body
Explain how antibiotic medications are prescribed and the dosage given