extra nipple

extra breast tissue

no breast

bacterial (staph aureus), neutrophils mixed with milk

secondary to systemic disease or infectious microorganisms

in perimenopausal breasts, infiltration of lymphocytes and plasma cells

clogs lactiferous ducts, resulting in abscess formation

can clinically and radiographically resemble cancer (hard mass, calcifications)

reaction to silicon globules

benign, non-neoplastic, present in up to 50% of women, cyclical pain and irregularly lumpy breasts; histologically, there are non-proliferative and proliferative versions

cyst formation, fibrosis, apocrine metaplasia

cyst formation, fibrosis, apocrine metaplasia, usual ductal hyperplasia (without atypia)

aggregates of acinar structure

radial arrangement of dilated glands peripherally

intraductal neoplastic low grade lesion with architectural and cytologic features suggestive but not diagnostic of low grade ductal carcinoma in situ (DCIS)

some features of lobular carcinoma but not extensive enough

relative risk of subsequent breast cancer = 1x

relative risk of subsequent breast cancer = 1.5-2x

relative risk of subsequent breast cancer = 3-5x

subareolar mass may present with clear or bloody nipple discharge, no increase in cancer risk

intraductal and incidental (no mass), slight increase in cancer risk

breast enlargement in men due to imbalance between estrogen and androgens, pathologic from cirrhosis and medications

milky nipple discharge in men from pituitary tumor or hypothyroidism

most common benign tumor of breast, young (20s-30), painless, benign glands and stromal proliferation of low or at most moderate cellularity

rare, biphasic, fibroepithelial tumor (like fibroadenoma), neoplastic stroma w/ benign ductal structures, variable malignant potential, widely excised or simple mastectomy w/o lymph node dissection

most common malignancy to metastasize to breast tissue

uncommon but can occur in the breast

agressive, infiltrative tumor

B-cell lymphoma

rare but unique T-cell lymphoma of the breast