Endocrine System
paired glands suspended in the scrotum
Testes
Located in the anterior neck; produces key hormones for metabolism
Thyroid Gland
Produces the hormones that are stored in the posterior pituitary
Hypothalamus
A mixed gland, located behind the stomach and close to the small intestine
Pancreas
bilobed gland located in the sella turcica
Pituitary Gland
found in the pelvic cavity of the female, concerned with ova and female hormone production
Ovarie
found in the upper thorax overlying the heart; large during youth
Thymus gland
found in the rood of the third ventricle of the brain
Pineal gland
Define Hormones
chemical messengers
Define target cell
A cell that have specific receptor for that hormone to respond in a specific way
Stimulates hormone released by Adrenal Cortex
Adrenocorticotropic Hormone (ACTH)
Secrete chemical messenger that travel in the bloodstream
Endocrine gland
Chemical signaling that effects neighboring cells
Paracrine
Release their secretion through a duct that delivers the secretion to the target location
Exocrine
Release their secretion into the surrounding fluid, from which it enters the bloodstream or lymph to travel to distant cells
Endocrine
Chemical signal that elicit a response in the same cell that secreted it
Autocrine
Tissues or organ that secretes hormones into the blood and lymph without ducts such that they may be transported to organs distant from the site of secretion
Endocrine Gland
Promotes growth of body tissues and is secreted by Anterior Pituitary gland
Growth Hormone (GH)
Promotes milk production and secreted by Anterior Pituitary
Prolactin (PRL)
Stimulates thyroid hormone release and secreted by Anterior Pituitary
Thyroid Stimulating Hormone (TSH)
Stimulates kidney to reabsorb water and is secreted by Posterior Pituitary
Antidiuretic Hormone (ADH)
Stimulates uterine contractions and mammary gland cells; secreted by Posterior pituitary
Oxytocin
Stimulates egg and sperm production and secreted by Anterior Pituitary
Follicle-stimulating Hormone (FSH)
Stimulates ovaries and testes and secreted by Anterior Pituitary
Luteinizing hormone (LH)
Stimulates Adrenal Cortex and secreted by Anterior Pituitary
Adrenocorticotropic Hormone (ACTH)
Stimulates T-cell development and secreted by Thymus
Thymosin
Decrease blood glucose level and secreted by Pancreas
Insulin
Increase blood glucose level and secreted by pancreas
Glucagon
Involved in day and night cycles
Melatonin
Supports sperm formation and male secondary sex characteristics
Testosterone
Triggers the anterior pituitary to secrete hormones from Hypothalamus
Releasing hormones
Stimulates and maintains metabolic processes, activate T3 and secreted by Thyroid Gland
Thyroxine (T4)
Lowers blood calcium levels and secreted by Thyroid Gland
Calcitonin
Raises blood calcium level
Parathyroid hormone (PTH)
also known as T 3 , is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate
Triiodothyroxine
blood-pressure raising hormone secreted by the medulla of the adrenal (medulla) gland
Epinephrine
similar to epinephrine in its physiological effects but acts to regulate regular physiologic activity rather than being released in response to stress. Secreted by Adrenal (medulla) gland
Norepinephrine
Promotes glucose synthesis, reduces inflammation, increase blood glucose
Corticosteroids
Stimulates uterine lining growth and development of female secondary sex characteristics
Estrogens
Promotes uterine lining growth
Progesterone
Release in response to stressors by the Adrenal Cortex
Cortisol
Increases blood Na+ levels and secreted by adrenal cortex
Aldosterone
Insulin deficit diabetes due to autoimmune disease that usually causes destruction of beta cells, and is treated with insulin replacement therapy.
Type I Diabetes Mellitus
non-insulin-dependent diabetes, and usually is caused by a combination of genetic/developmental predisposition, environmental factors, and lifestyle factors that lead to insulin receptors (or the 2ndmessenger systems) malfunctioning. This can also lead to beta cells becoming nonfunctional.
Type II Diabetes Mellitus
produces leptin and other hormones that regulate appetite and assist blood sugar regulation.
Adipose Tissue
caused by loss of insulin production or insulin resistance.
Diabetes Mellitus
Low blood sugar, causes weakness and sometimes fainting.
Hypoglycemia
Retain sodium and increase Blood Pressure
Mineralocorticoids
Promotes glucose production from fats and proteins, and suppress the immune system
Glucocorticoids
Hormones that stimulate other endocrine glands
Tropic Hormone
Enlargement of the thyroid gland, can occur due to tumors(pituitary or thyroid), and dietary deficiency of iodine (follicles swell with unusable colloid; TSH stays high).
Goiter
undrproducing
Hypo
overproducing
Hyper
RH stands for and is made from hypothalamus; example GHRH
Releasing hormone
IH stands for and is made from hypothalamus; example GHIH
Inhibiting Hormone
When a target cell decrease the number of receptors makings cell less sensitive to hormone
Down-Regulation
When a target cell increase the number of receptors making cell more sensitive to hormone
Up-Regulation
Hormone release caused by another hormone
Hormonal Stimulus
Hormone release caused by neural input
Neural Stimulus
The concentration of the substance when the gland regulates that triggers or inhibits release of the hormone due to altered levels
Humoral Stimulus
The amount that the gland can produce and the time for half of the hormone molecules to degrade(half-life)
Concetration
When more than one hormone produces the effect at its target cell and their combine effects implifies
Synergism
Situation where one hormone needs another hormone to produce its full effect
Permissiveness
Water soluble hormones
Peptide/Amino Acid Hormone
Hormone-receptor combination directly affects the cells DNA, and directly initiates or inhibits some cell function
Direct Gene Activation
Lipid soluble hormone
Steroid Hormone