Anticoagulant: Warfarin Flashcards


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created 2 years ago by AWilson274
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1

Anticoagulant

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2

Warfarin

  1. Coumadin
  2. Jantoven

3

Mechanism of Action: Warfarin

Warfarin completely inhibits the C1 subunit of multi-unit Vitamin K epoxide reductase (VKORC1) enzyme complex causing depletion of clotting factors 2, 7, 9, 10 and protein C and S.

4

FDA Indications: Warfarin

  • Atrial Fibrillation
  • Prosthetic cardiac valve component embolism
  • Pulmonary embolism
  • Thrombosis
  • Venous thromboembolism

5

Adverse Effects of Warfarin

  • Unusual and unexpected bleeding
  • Alopecia
  • Fever
  • N/D
  • Dermatitis

6

What Pregnancy Category is Warfarin?

Pregnancy Category X

7

Patient Counseling Tips

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8

Patients should be advised to take Warfarin at the _________ everyday without regard to food.

Sametime

9

Patients taking Warfarin should be advised that they will need to have their blood tested frequently to check their __________.

INR

10

Patients taking Warfarin should be advised to not make changes in diet such as eating large amounts of green leafy foods as they contain a large amount of ____________.

Vitamin K

11

Patients taking Warfarin are advised to not drink ______.

Alcohol

12

Patients taking Warfarin should be advised that they can experience _____ _____ syndrome that can cause toes to become painful and purple in color.

Purple Toe Syndrome