NOTE: Has some COX-2 selectivity
Mechanism of Action: NSAIDs
NSAIDS inhibit COX-1 and COX-2 which leads to reduction of prostaglandins in peripheral tissue.
FDA Indications: Meloxicam
- Rheumatoid Arthritis
Adverse Effects of NSAIDs
- Abdominal pain
Patients taking NSAIDS with increased selectivity for COX-2 have less risk for GI complications but an increased risk for CV issues.
Patient Counseling Tips
Patients should be advised that NSAIDs can increase _______ _______.
NOTE: Patients should monitor regularly.
Patients should be advised that NSAIDs should not be used with blood ________ agents as the risk of GI bleeding and ulcers is increased.
Blood Thinning Agents
Patients should be advised that NSAIDs can cause water and fluid to accumulate in the body leading to _________.
NSAIDS can cause _______ therefore patients on this medication should limit sun exposure.
Patients should be advised that NSAIDs have an increased risk of bleeding and should not be used before any _________.
NSAIDs should be taken with food to decrease _______ upset.
Patients taking NSAIDs should not use _____ without consulting a doctor.
Patients taking NSAIDs should be advised that _____ weeks may be required before improvements in arthritis pain is improved.