Angiotensin Receptor Blockers (ARB)
Mechanism of Action: ARBs
ARBs block Angiotensin II from binding to the Angiotensin II type-1 (AT1) receptor on the vascular smooth muscle, preventing vasoconstriction.
FDA Indications: ARBs
- Diabetic Nephropathy
- Cerebrovascular accident (stroke) in patients with LV hypertrophy prophylaxis
Adverse Effects of ARBs
- Upper Respiratory Infection (nasal congestion)
What is the Pregnancy Category of ARBs?
Pregnancy Category D
Patient Counseling Tips
Patients should be counseled that ARBs can cause ________ _________ if taken while pregnant.
While on ARBs women in child-bearing ages should use _________ ________.
Patients on ARBs should be counseled that these medications can increase the amount of ________ in the body.
NOTE: Patients should be encouraged to not use potassium supplements or salt substitutes unless advised by PCP.
Patients on ARBs should be advised to get emergency help if they experience the following symptoms signifying an allergic reaction:
- Swelling of the lips/face/tongue/throat
- Difficulty breathing
Patients on ARBs should be informed that they can develop a dry, hacking ________.
NOTE: Patients should notify PCP if this happens