Atypical Antidepressant/Serotonin Modulator
Mechanism of Action of Trazodone
Trazodone inhibits serotonin reuptake by brain synaptosomes therefore increasing the behavioral effects of the serotonin precursor 5-hydroxytryptophan (5-HT)
FDA Indications: Trazodone
Major Depressive Disorder
RX Prep Book:
Trazodone is RARELY used for depression due to sedation. It is mainly used off-label for sleep.
Adverse Effects of Trazodone
- Xerostomia (dry mouth)
- Somnolence (sleepiness)
- Blurred Vision
- Feeling Nervous
Patient Counseling Tips
Patients should be advised that Trazodone causes drowsiness and should be taken at ____________.
Male patients taking Trazodone should be counseled to contact PCP if they experience an _________ lasting longer than 4 hours.
Patients should be advised to take Trazodone at bedtime with food to enhance ________________.
True or False
Patients should avoid alcohol while taking this medication.
Patients taking Trazodone should be advised to use caution when operating machinery as it can cause severe __________.