Beta Blockers Flashcards
Beta-1 Selective Blockers
Mechanism of Action: Beta-1 Selective Blocker
Beta-1 Selective Blockers are cardioselective beta-1 adrenergic receptor blocker which:
1. Decreases HR and CO
2. Decreases SBP and DBP
3. Decreases reflex orthostatic tachycardia
FDA Indications: Metoprolol Tartrate
- Acute Myocardial Infarction
- Angina Pectoris
FDA Indications: Metoprolol Succinate
- Angina Pectoris
- Congested Heart Failure (CHF)
Adverse Effects of Beta 1-Selective Blockers
- Bradyarrhythmia (slow heart rate)
Non-Selective Beta-Blocker and Alpha-1 Blocker
Mechanism of Action: Non-Selective Beta-Blocker and Alpha-1 Blocker
Non-Selective Beta-Blocker and Alpha-1 Blocker are non-selective beta-adrenergic blocking agent with alpha-1 adrenergic blocking activity. This activity results in:
- A reduction in CO
- Reduces reflex orthostatic tachycardia
FDA Indications: Carvedilol
- Heart Failure
- Impaired Left Ventricular Function - Myocardial Infarction
Adverse Effects of Non-Selective Beta Blockers/Alpha-1 Blockers
- Abnormal Weight Gain
- Erectile Dysfunction
Patient Counseling Tips for Beta Blockers
Patients should be advised to take Beta Blockers at the _________ everyday.
Patients taking Beta Blockers should not __________ discontinue the medication as it may worsen condition.
Patients should be advised that Beta Blockers can cause the following side effects:
- Sexual problems (rare)
Patients with diabetes should be advised that Beta Blockers can _________ hypoglycemic effects.
NOTE: Beta Blockers can mask symptoms of hypoglycemia such as palpitations, anxiety, and shakiness. You will still experience sweating and hunger.
Which 2 Beta-1 Selective Blockers must be taken with food or immediately following meals for increased absorption?
- Metoprolol Tartrate (Lopressor)
- Metoprolol Succinate (Toprol XL)
Which Non-Selective Beta Blocker/Alpha-1 Blocker MUST be taken with food to decrease the rate of absoprtion and the risk of orthostatic hypertension?
1. Carvedilol (Coreg)