Beta Blockers Flashcards


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1

Beta Blockers

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2

Beta-1 Selective Blockers

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Mechanism of Action: Beta-1 Selective Blocker

Beta-1 Selective Blockers are cardioselective beta-1 adrenergic receptor blocker which:

1. Decreases HR and CO

2. Decreases SBP and DBP

3. Decreases reflex orthostatic tachycardia

4

Metoprolol Tartrate

Lopressor

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FDA Indications: Metoprolol Tartrate

  • Acute Myocardial Infarction
  • Angina Pectoris
  • Hypertension

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Metoprolol Succinate

Toprol XL

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FDA Indications: Metoprolol Succinate

  • Angina Pectoris
  • Congested Heart Failure (CHF)
  • Hypertension

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Adverse Effects of Beta 1-Selective Blockers

  • Bradyarrhythmia (slow heart rate)
  • Hypotension
  • Dizziness

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Non-Selective Beta-Blocker and Alpha-1 Blocker

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Mechanism of Action: Non-Selective Beta-Blocker and Alpha-1 Blocker

Non-Selective Beta-Blocker and Alpha-1 Blocker are non-selective beta-adrenergic blocking agent with alpha-1 adrenergic blocking activity. This activity results in:

  1. A reduction in CO
  2. Reduces reflex orthostatic tachycardia

11

Carvedilol

Coreg

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FDA Indications: Carvedilol

  • Heart Failure
  • Hypertension
  • Impaired Left Ventricular Function - Myocardial Infarction

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Adverse Effects of Non-Selective Beta Blockers/Alpha-1 Blockers

  1. Bradyarrhythmia
  2. Hypotension
  3. Abnormal Weight Gain
  4. Hyperglycemia
  5. Erectile Dysfunction
  6. Diarrhea
  7. Dizziness

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Patient Counseling Tips for Beta Blockers

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15

Patients should be advised to take Beta Blockers at the _________ everyday.

Sametime

16

Patients taking Beta Blockers should not __________ discontinue the medication as it may worsen condition.

abruptly

17

Patients should be advised that Beta Blockers can cause the following side effects:

  • Dizziness
  • Fatigue
  • Sexual problems (rare)

18

Patients with diabetes should be advised that Beta Blockers can _________ hypoglycemic effects.

mask

NOTE: Beta Blockers can mask symptoms of hypoglycemia such as palpitations, anxiety, and shakiness. You will still experience sweating and hunger.

19

Which 2 Beta-1 Selective Blockers must be taken with food or immediately following meals for increased absorption?

  1. Metoprolol Tartrate (Lopressor)
  2. Metoprolol Succinate (Toprol XL)

20

Which Non-Selective Beta Blocker/Alpha-1 Blocker MUST be taken with food to decrease the rate of absoprtion and the risk of orthostatic hypertension?

1. Carvedilol (Coreg)