PDA II Exam II Lee Flashcards


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created 2 years ago by YaniseHurt
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1

What are the monoamines

DA, NE, E, 5-HT

2

Which monoamines are within the CNS

DA

5 HT

3

Where in the periphery is 5 HT located

Platelets

GI Tract

4

Where in the periphery is DA located

Enteric Nervous system

GI Tract

Adrenal Medulla

5

What cells produce 5 HT

Raphe nuceli

6

Where is the majority of MAO located as it pertains to 5 HT

Within the presynaptic terminal

7

Why

Because 5 HT enters via re-uptakes

8

What isoform of MAO is metabolized by 5 HT

MAO-A

9

Which isoform of MAO is metabolized by DA

MAO-B

10

Where are they located

They are mito enzymes located in

Nerve endings

Liver

Kidneys

Intestinal Mucosa

11

Which regulating functions are seen from 5HT

Mood

Cognition

Appetite

GI Motility

Emetic Response

Platelet Aggregation

Sleep-Wake Cycle

12

5-HT-1 Rec are considered

Autoreceptors

13

What are they

A B C D

14

Are they stimulatory or inhibitory

Inhibitory Gi

15

What is the purpose of Ca2+

Allows vesicles to flow out of the cell

16

What kind of NT is 5-HT2

Gq

17

What is the Gq cascade

PLC--DAG/IP3--CA2+ and PKC