Anticonvulsant/Antineuralgic Flashcards

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1

Drug Class of Gabapentin

Anticonvulsant/Antineuralgic

2

Gabapentin

  1. Neurontin
  2. Gralise

3

Mechanism of Action of Gabapentin

The exact MOA of Gabapentin is unknown.

NOTE: Gabapentin is structurally related to the GABA neurotransmitter but it does NOT interact with GABA receptors and is NOT and inhibitor of GABA uptake or degradation.

4

FDA Indications of Gabapentin

  • Partial seizure (Adjunct Therapy)
  • Postherpetic Neuralgia (Neuropathy)

5

Most Common Adverse Effects of Gabapentin

  • Somnolence (excess sleepiness)
  • Dizziness
  • Ataxia (impaired coordination)
  • Fatigue
  • Viral Disease

6

Patient Counseling Tips

...

7

Patients taking Gabapentin should be advised that they should take caution when operating machinery or when mental alertness is required because Gabapentin causes _________.

Drowsiness

8

Patients taking Gabapentin should be advised to NOT discontinue drug abruptly because of risk of increased _________ frequency.

Seizure

9

Patients should be tapered off of Gabapentin over a ____ week period.

1 week