Loop Diuretics Flashcards

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1

Furosemide

Lasix

2

Bumetanide

Bumex

3

Mechanism of Action of Loop Diuretics

Loop diuretics inhibit reabsorption of sodium and chloride in the thick ascending limb of the loop of henle.

4

FDA Indications

  • Edema
  • Edema associated with CHF, Cirrhosis of the Liver, and Renal Disease
  • Hypertension
  • Pulmonary Edema

5

Most Common Adverse Effects of Loop Diuretics

  • Increased UA, BG, TG, Total Cholesterol, Increased HCO3
  • Decreased K, Mg, Na, Cl, Ca
  • Orthostatic Hypotension
  • Ototoxicity
  • Photosensitivity

6

Allergy: Loop Diuretics

Sulfa Allergy

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BBW of Loop Diuretics

Extreme diuresis resulting in fluid and electrolyte depletion

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Patient Counseling Tips

...

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Loop Diuretics help your body to remove extra fluid. Taking it consistently even if you feel better will help with ______ and _______.

SOB and Swelling

10

Patients should take Loop Diuretics early in the day (morning) to prevent _________.

Nocturia (using the restroom in the middle of the night)

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Loop diuretics can cause orthostatic hypotension. Patients should be counseled to get up _________ if they have been sitting or lying down.

slowly

12

If GI upset occurs when taking Loop Diuretics', patients can take the medicine with _____ or ________.

Food or Milk

13

While on Loop Diuretics, patients should NOT take which drugs without consulting PCP first?

  1. Cough or Cold Medicines
  2. Antacids
  3. Laxatives'
  4. Antidiarrheal
  5. NSAIDs

NOTE: Can have an impact on electrolyte levels or sodium and water reabsorption.

14

Patients should avoid overexposure to sunlight as Loop Diuretics' can cause __________.

Photosensitivity