Furosemide
Lasix
Bumetanide
Bumex
Mechanism of Action of Loop Diuretics
Loop diuretics inhibit reabsorption of sodium and chloride in the thick ascending limb of the loop of henle.
FDA Indications
- Edema
- Edema associated with CHF, Cirrhosis of the Liver, and Renal Disease
- Hypertension
- Pulmonary Edema
Most Common Adverse Effects of Loop Diuretics
- Increased UA, BG, TG, Total Cholesterol, Increased HCO3
- Decreased K, Mg, Na, Cl, Ca
- Orthostatic Hypotension
- Ototoxicity
- Photosensitivity
Allergy: Loop Diuretics
Sulfa Allergy
BBW of Loop Diuretics
Extreme diuresis resulting in fluid and electrolyte depletion
Patient Counseling Tips
...
Loop Diuretics help your body to remove extra fluid. Taking it consistently even if you feel better will help with ______ and _______.
SOB and Swelling
Patients should take Loop Diuretics early in the day (morning) to prevent _________.
Nocturia (using the restroom in the middle of the night)
Loop diuretics can cause orthostatic hypotension. Patients should be counseled to get up _________ if they have been sitting or lying down.
slowly
If GI upset occurs when taking Loop Diuretics', patients can take the medicine with _____ or ________.
Food or Milk
While on Loop Diuretics, patients should NOT take which drugs without consulting PCP first?
- Cough or Cold Medicines
- Antacids
- Laxatives'
- Antidiarrheal
- NSAIDs
NOTE: Can have an impact on electrolyte levels or sodium and water reabsorption.
Patients should avoid overexposure to sunlight as Loop Diuretics' can cause __________.
Photosensitivity