Thyroid Drugs Flashcards


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created 2 years ago by AWilson274
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1

Drug Class of Levothyroxine

Thyroid Hormone

2

Levothyroxine Sodium (T4)

1. Synthroid

2. Levoxyl

3. Levothroid

3

FDA Indication

Hypothyroidism

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Mechanism of Action Levothyroxine

The exact MOA of Levothyroxine is unknown, however, when administered, T4 diffuses into the cell nucleus and binds to thyroid receptor proteins attached to DNA resulting in:

1. a regulation of growth and development

2. an increases in metabolic rate

3. inhibition of the secretion of thyrotropin by the pituitary

4. various effects on lipid and carbohydrate metabolism

5

Adverse Effects of Levothyroxine

Extremely rare other than those adverse effects occurring due to overdosing.

6

Overdosing from Levothyroxine can result in a hypermetabolic state with the following symptoms:

1. Fever

2. HypOglycemia

3. HF

4. Fluid loss

5. Tachycardia

6. Anxiety

7. Insomnia

7

Contraindication of Levothyroxine

Uncorrected adrenal insufficiency

8

BBW of Levothyroxine

When used off-label for obesity or weight reduction Levothyroxine can cause extreme toxicity.

  • NOT to be used to treat obesity and weight loss
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Patient Counseling Tips for Levothyroxine

...

10

Levothothyroxine must be taken with _________

Water

NOTE: Water should be drank consistently for at least 60 minutes for better absoprtion.

11

Take Levothyroxine ____ minutes before breakfast

60 minutes

12

TRUE or FALSE

Different brands of Levothyroxine may NOT work the same.

TRUE

13

If taken at bedtime, it MUST be take at least _____ hours after last meal.

3 hours

14

How often should thyroid levels be tested when receiving thyroid suppplementation?

Annually

15

The full effect of Levothyroxine is usually delayed. How long does it usually take for the full effect of Levothyroxine to be observed?

1-2 months

16

TRUE or FALSE

Levothyroxine can be taken 60 minutes before breakfast OR at bedtime (at least 3 hours after last meal)

TRUE