Principles of Pharmacology

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created 10 months ago by arens
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updated 9 months ago by arens
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Epinephrine 1:10,000

1 mg IV/IO; repeat every 3-5 minutes

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Amiodarone

300 mg IV/IO

May repeat one 150 mg in 5 minutes

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Atropine

0.5 mg IV q 3-5min PRN

Max dose = 3 mg total dose

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Epinephrine 1:1,000

0.2 - 0.5 mg SC/IM q 5 - 10 min PRN

Max dose = 1 mg/dose

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Nitroglycerine

0.3 - 0.6 mg SL q 5 minutes (Usual dose is 0.4 mg)

Max dose = 3 doses within 15 minutes

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Ketamine

0.1-0.35 mg/kg/dose IV x 1; May repeat per protocols

OR

0.5-1 mg/kg/dose IN x 1; May repeat 0.25-0.5 mg/dose IN x 1 after 10-15 minutes if no response.

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Morphine

2.5 - 10 mg SC/IM/IV q 2-6h PRN

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Fentanyl

50 - 100 mcg IV/IM q 1-2h PRN

1-2 mcg/kg/dose IN q 1h PRN; Max dose = 100 mcg/dose

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Adenosine

6 mg IV x 1

May repeat 12 mg IV x 1

All doses given rapid IV push over 1-3 seconds

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Magnesium Sulfate

1-2 g IV over 15 min x 1 (without cardiac arrest)

OR

1-2 g IV over 1-2 min x 1 (with cardiac arrest)

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Dextrose

10-25 grams/dose

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Aspirin

162-325 mg PO x 1

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Lidocaine

1 - 1.5 mg/kg/dose IV/IO x 1

Maximum dose = 3 mg/kg/total dose

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Naloxone (Narcan)

0.4 - 2 mg SC/IM/IV q 2-3 min PRN

1 mg in each nostril x 1 IN may repeat q 3-5 min if symptoms recur

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Diazepam (Valium)

Anxiety

  • 2-10 mg IM/IV q 3-4h PRN

Sedation

  • 5-15 mg IV x 1

Seizure

  • 5-10 mg IV q 5-10 min PRN
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Lorazepam (Ativan)

Anxiety

  • 2-6 mg IM/IV divided BID-TID; Max 10 mg/day

Sedation

  • 0.044-0.05 mg/kg/dose IV x 1; Max 4 mg/dose
  • 0.05 mg/kg/dose IM x 1; Max 4 mg/dose

Seizure

  • 4 mg IV x 1; May repeat x 1 after 10-15 min
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Midazolam (Versed)

Sedation

  • 1 mg IV x 1 q 2-3 min; Max dose 2.5 mg/dose
  • 0.1 mg/kg/dose IN x 1

Seizure

  • 5 mg x 1 IN; May repeat x 1 after 10 min; Max dose 2 doses/single episode
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Ondansetron (Zofran)

4-8 mg IV/IM q 8 hours PRN

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Promethazine (Phenergan)

12.5 - 25 mg IM/IV q 4-6h PRN

Maximum dose = 50 mg/dose IM; 25 mg/dose IV; 100 mg/day