Drug Quiz 2_Pearls

Helpfulness: 0
Set Details Share
created 12 days ago by brandibyler
updated 12 days ago by brandibyler
show moreless
Page to share:
Embed this setcancel
code changes based on your size selection


  • BM w/in 15-60 min after rectal admin and 6-12 h of oral admin
  • Not for chronic use (PEG 3350 is preferred for chronic bc better safety).
  • Due to MOA may not be effective in patients with SC damage/paralysis from polio

Carbamide peroxide

  • one type of drop or cerumen removal method is not better than others
  • Cerumenolytics are the trtmt of choice for earwax impaction
  • Avoid ear candeling
  • Avoid confusion: similar products for the trtmt of swimmer’s ear contain isopropyl alcohol.
  • Available in 10% solution (Gly-Oxide) for oral rinse for mouth, gum, or dental irritation.


  • Multiple products available, often in combo w/ other AI
  • Can cause varying degrees of euphoria, hallucinations (usually 100-400 mg), temporary psychosis, alterations in consciousness, and out-of-body experiences (usually >600 mg) = potential to abuse
  • Many pharmacies voluntarily only allow purchases by adults >18 y of age to reduce abuse
  • Not for persistent or chronic cough or for self-care in children <4 yo
  • serotonin syndrome w/ use of proserotonergic drugs.


  • Available OTC in many different products
  • some brand name products w/ same name contain meclizine instead of dimenhydrinate
  • Read product labeling carefully to confirm A
  • Take 30-60 min before, and continuously during activities producing nausea;
  • More effective as prevention than for treatment.
  • Parenteral formulation available for IM or IV admin by HCP if symptoms severe

Evening Primrose Oil

  • No difference in efficacy between placebo and evening primrose oil for eczema
  • AE more common in the evening primrose group (mild GI distress)
  • Used for breast pain, menstrual symptoms, diabetic nephropathy, and rheumatoid arthritis, despite the lack of evidence as to its efficacy
  • No evidence for use of this drug for any health condition.

Ferrous Sulfate

  • Decreasing dose = decrease GI distress
  • Sustained-release products may reduce AE bc lower iron absorption as iron is absorbed proximal to the jejunum.
  • Vitamin C enhances absorption, but avoid orange juice containing calcium.
  • Various prescription and OTC products, as well as other iron salts that contain different amounts of elemental iron, are available; confirm appropriate elemental iron for dosing purposes.
  • Contraindicated in patients with iron overload, such as those with hereditary hemochromatosis or transfusion-dependent anemias.

Flaxseed Oil

  • Plant source of Omega 3
  • Reduces LDL and TG; further study needed before flaxseed oil can be routinely recommended.
  • Contains fiber used for constipation
  • Being studied as a treatment for cancer, diabetes, dry skin, constipation, and various other conditions; no conclusive evidence of efficacy yet


  • Little evidence for effectiveness for acute coughs in adults or children
  • few AE; may be beneficial in some patients
  • Multiple combo products available, including guaifenesin/codeine syrup that can be dispensed OTC by pharmacists in a majority of states
  • Double-check for therapeutic duplication.
  • Labeling of various OTC products list varying minimum age limits for this product, many manufacturers voluntarily relabeled products to state “do not use in children <4 years of age,” but data exist for dosing down to 2 y of age.

Human Papilloma Virus




  • Data in children is limited but has been used safely in many trials (eg, for mild acute diarrhea associated with rotavirus infection).
  • Has been studied for radiation-induced diarrhea
  • Individual effects vary by strain
  • If one product fails to produce desired effect, alternative product with different mix of strains may still be beneficial
  • For antibiotic-assoc. diarrhea, take at least 2 h after the antibiotic dose to ensure survival, and continue 7-14 d after completion of antibiotic
  • Refrigeration requirements vary by product
  • If refrigeration required, can be stored at room temperature for up to 1 wk.


  • Treats symptoms, not cause, of diarrhea.
  • This drug, w/ or w/o antibiotic, is preferred trtmt of traveler’s diarrhea
  • Not to be used as primary therapy for bacterial enterocolitis, dysentery, pseudomembranous colitis associated with the use of broad-spectrum antibiotics, or acute ulcerative colitis (other primary therapy required).
  • High doses (up to 60 mg) have been used w/o med supervision for opioid withdrawal, leading to CNS depression and intestinal blockage, and should not be recommended for OTC use.
  • Special alert issued June 2016: cardiac events caused by use of higher than recommended doses, including through abuse or misuse of the product.

Measles, Mumps, & Rubella



Miconazole (vaginal)

  • All topical imidazole antifungals are considered equivalent to one another, but more effective than nystatin
  • Oral product available via prescription for oropharyngeal candidiasis.

Omega-3-Acid Ethyl Esters

  • Rx fish oil concentrate capsules (Lovaza) are more concentrated than OTC product = fewer capsules per dose
  • Trtmt of hypertriglyceridemia with this drug offers a better tolerability profile for patients as compared with other drugs, such as gemfibrozil and niacin
  • equivalent to gemfibrozil in efficacy
  • Different formulations contain variable amounts of EPA and DHA
  • Typically, a 1-g capsule contains between 200 and 950 mg of EPA and DHA
  • fishy aftertaste and fishy burps
  • Enteric-coated product, taking the product with meals or at bedtime, or refrigerating or freezing the product may improve palatability and reduce aftertaste
  • Beta-blockers, thiazides, and estrogens increase triglycerides, DC if possible


  • Use the same brand to complete series
  • Adacel not for children <11 yo
  • Daptacel not for children <6 wk or >6 yo of age
  • Avoid confusing Tdap and DTaP products
  • Vaccination with DTaP may need to be delayed in children with known or suspected neurological conditions until the condition is evaluated, treated, and stable.
  • Local reactions may be more frequent after the 4th or 5th dose of the series.

Phosphorated carbohydrate






Polyethylene glycol









St John's Wort






Undecylenic acid






Zinc oxide