FINAL EXAM PRACTICE EXAM 2 (Clin Chem)

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1

"A progressive systemic skeletal disease characterized by low bone mass and micro architectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptible to fracture" describe which of the following disesase?

Osteoporosis

2

Biomarkers of bone formation include which of the following?

Osteocalcin

3

Which of the following is the effect of increased parathyroid secretion?

Increased intestinal absorption of calcium

4

Which of the following laboratory results best represents a patient with Paget's disease?

Decreased urinary hydroxyproline, increased serum alkaline phosphatase

5

A patient with Addison't disease would present with which of the following?

Low sodium, high potassium levels

6

Cushing's syndrome is characterized by which of the following?

Corticosteroid excess (in blood)

7

Once produced, the thyroid hormones are stored as thyroglobulin in which of the following?

...

8

Oxytocin and antidiuretic hormone (ADH) are hormones that are released by the:

Posterior pituitary

9

Pituitary gigantism is associated with which of the following?

GH excess

10

Pituitary secretion of ACTH is inhibited by elevated levels of:

Cortisol

11

Primary hypothyroidism may be due to all of the following EXCEPT:

Pituitary adenoma

12

Select the principle estrogen produced by the ovaries and measured to elevate the ovarian function.

Estradiol

13

Which of the following hormones is useful in identifying women with ectopic pregnancies or abnormal intrauterine pregnancies?

Human chorionic gonadotropin

14

Which of the followng is an anterior pituitary hormone?

ACTH

15

Which statement below about patients with Addison's disease is true?

Serum levels of ACTH are high

16

A gastrinoma is classified as which of the following?

Neuroendocrine tumor (NET)

17

Characteristics of the ideal cardiac marker include all of the following EXCEPT:

Marker must return to normal in a relatively short period of time.

18

Risk factors for the development of coronary heart disease include which of the following?

Hypertension, abdominal obesity, low HDL-C, high serum levels of CRP, and elevated levels of homocysteine.

19

The significance of CRP in the arterial wall is described as which of the following?

It predicts the severity of atherosclerosis and is able to bind to damaged membranes and lipids

20

Which of the following represents an accepted protocol for making a diagnosis of acute myocardial infarction?

Patient history, EKG (or ECG), serial sampling of blood for measurement of cTnI

21

A breakdown product of bilirubin metabolism that is produced in the colon from the oxidation of urobilinogen by microorganism is:

Urobilin

22

A model for End-Stage Liver disease staging system to predict prognosis in cirrhosis uses the following laboratory determinations EXCEPT:

Aspartate transaminase

23

Alcoholic liver disease that follows six months to a year of moderate consumption, few lab abnormalities, and is reversible with abstinence from alcohol is termed:

Alcoholic fatty liver

24

Bile formed in the liver is stored in the:

Gall bladder

25

In obstructive liver disease, the following test results are found:

Feces: urobilinogen decreased; urine: bilirubin: positive; serum: conjugated bilirubin increased

26

Kernecterus is the abnormal accumulation of bilirubin in:

Brain tissue

27

Nonalcoholic steatohepatitis is characterized by all of the following EXCEPT:

AST greater than ALT

28

The first serological marker of Hepatitis B is:

HBsAg

29

The following disease is a recessive disorder of copper metabolism, which result in the accumulation of copper in the liver.

Wilson's disease

30

Viral hepatitis that results in the largest percentage of chronic hepatitis is:

Hepatitis C

31

What is the most common cause of unconjugated hyperbilirubinemia?

Neonatal physiologic jaundice

32

Which is a characteristic of unconjugated bilirubin?

It a not water-soluble

33

Which of the following would be classified as prehepatic jaundice?

Congestive heart failure

34

Which of the statements regarding bilirubin metabolism is true?

It is produced from the destruction of RBCs

35

A 25-year-old female visits her physician complaining of lethargy and wants to take a nap all the time. Her physician orders laboratory tests and results are shown below. Which of the following conditions best represent this patient's status?

Iron deficiency anemia

36

A patient with acute intermittent porphyria is deficient in which enzyme?

Hydroymethylbilane synthase

37

Free erythrocyte protoporphyrin levels are useful for assessing exposure to which of the following metals?

Lead

38

The following laboratory results are consistent with which of the following conditions?

Acute intermittent porphyria

39

The following statement best describes which of the terms listed below? The pathological condition that develops when iron intake falls below the amount required for red blood cell production and iron reserves become depleted.

Anemia

40

What is the primary storage form of iron?

Ferritin