Cardiopulmonary Anatomy & Physiology: Essentials of Respiratory Care: RTAD 122 Respiratory Physiology Diffusion Key Terms Flashcards


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Des Jardins Chapter 4
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1

Internal / external respiration

Internal respiration-metabolic use of oxygen by cell and release of carbon dioxide

External respiration-exchange of gases between outside environment and the lungs

2

Dalton’s Law

each gas generates its own pressure the pressure to the total gas mix is equal to the sum of the partial pressure of each separate gas

3

Calculation of partial pressure of gas

...

4

Diffusion

Movement of gas molecules from an area of high concentration to low concentration-Alveolar capillary membrane

5

Equilibrium

When balance is reached and diffusion ceases

when opposing force are balanced

6

Partial Pressure of gases in (air, alveoli, and blood)

Air -159mmHg 159.0

Alveoli -100mmHg 100.0

blood- 95mmHg 95.0

7

Alveolar-capillary membrane

where gas exchange occurs

8

Water Vapor

water in a gaseous form

9

Barometric Pressure

total atmospheric pressure

10

Fick’s law (relation to gas diffusion)

Rate of gas transfer across a sheet of tissue is directly proportional to
the surface area of the tissue (A), to the diffusion constants (D), and to the
difference in partial pressure (P1 – P2) of the gas between the two sides of
the tissue and – Is inversely proportional to the T-thickness of the tissue

11

Henry’s and Graham’s law (in relation to Fick’s law)

Henry's Law-amount of gas that dissolves in a liquid at a given temperature is proportional to the partial pressure of gas

Graham's Law- the rate of diffusion of a gas through a liquid is inversely proportional to the square root of the gram molecular weight of the gas

12

Diffusion limited

Movement of gas across the alveolar wall is the function is of the integrity of the AC membrane itself

13

Perfusion limited

Transfer of gas across alveolar wall is function of the amount of blood that flows past alveoli

14

High altitude effect

Barometric pressure decreased

density of the different gases surrounding the earth decrease the higher you go

15

Effect of high altitude on PO2

atmospheric pressure decreases

16

Effect of high altitude on he PAO2 a

decreased

17

Effect of high altitude on and the PaO2

pressure will fall about 60mmHg

18

Effect of high altitude on Acclimatization

Physiological adjustment to a new environment a number of compensatory responses will develop as you ascend to a higher altitude if no acclimmatization occurs ther could be loss of consciousness in minutes due to oxygen tension

19

Effect of high altitude on Chronic
Hypoxia,

low blood oxygen content

20

Effect of high altitude on Polycythemia

develops from exposure to low concentration of oxygen for prolonged periods of time

21

Effect of high altitude on Erythropoietin

Hormone secreted by the kidneys used as a stimulant for RBC production from bone marrow which increases hemoglobin