Textbook of Biochemistry with Clinical Correlations: TCA cycle Flashcards


Set Details Share
created 10 years ago by kelley2wisc
123 views
Front: Enzyme Back: Action
updated 10 years ago by kelley2wisc
Grade levels:
Professional
show moreless
Page to share:
Embed this setcancel
COPY
code changes based on your size selection
Size:
X
Show:
1

Pyruvate Carboxylase

pyruvate--> oxaloacetate (C4)

Inhibits: none
Stimulates: acetyl CoA

2

Pyruvate Dehydrogenase

pyruvate--> acetyl CoA (C2)

Inhibits: acetyl CoA, NADH
Stimulates: CoA, NAD+, ADP, Pyruvate, Ca2+

3

Citrate Synthase

Acetyl CoA--> Citrate (C6)

4

Aconitase

Citrate (C6)-->isocitrate (C6)

5

Isocitate Dehydrogenase

Isocitrate--> α ketoglutarate (C5)

Inhibits: ATP, NADH
Stimulates: ADP, AMP

6

α ketoglutarate dehydrogenase

α Ketoglutarate (C5)--> Succinyl CoA (C4)

Inhibits: ATP, NADH, GTP, Succinyl CoA
Stimulates: Ca2+

7

Succinyl CoA Synthase

Succinyl CoA (C4)-->Succinate (C4)

8

Succinate dehydrogenase

Succinate (C4)--> Fumarate(C4)

9

Fumarase

Fumarate (C4)-->Malate (C4)

10

Malate Dehydrogenase

Malate (C4)-->oxaloacetate (C4)